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[实时颈动脉超声断层扫描定量和定性数据与标准多普勒检查、动脉造影及解剖病理学的对比验证。针对59例颈动脉内膜切除术]

[Validation of quantitative and qualitative data of real-time carotid echotomography in comparison with standard Doppler tests, arteriography and anatomopathology. On 59 carotid endarterectomies].

作者信息

Benhamou A C, Dutreix J L, Genre O, Arbeille P, Marchal C, Pourcelot L, Lapierre F, Dusorbier C

出版信息

J Mal Vasc. 1984;9(3):185-94.

PMID:6389743
Abstract

Findings on ultrasound, arteriography and pathology examinations were compared in 49 patients undergoing 59 carotid endarterectomies between December 1981 and April 1983. Carotid artery lesions were investigated routinely by cervical Doppler, high resolution rapid ultrasound and either direct or more usually venous arteriography (with photographic subtractions). Postoperative endarterectomy specimens were examined to determine the exact degree of stenosis, and also qualitatively (gross pathology and histology of ulcerations and thromboses, the biochemical nature of the plaques, etc.). With respect to detection, that is demonstration of the existence or not of an atheromatous lesion, the ultrasonographic findings could always (100% of cases) be correlated with pathology data. Qualitative analysis of atheromatous lesions showed certain to be diagnosed with ease: calcified, fibrous or chondroid and lipidic plaques, while those complicated by hemorrhage, ulceration or mural thrombosis were less constantly diagnosed by ultrasound imaging. Occlusive plaques were easily detected, while recent intraluminal thrombosis was more difficult to diagnose by ultrasound alone. In this case the combined use of Doppler is a valuable aid, and is a routine procedure, in fact, in the department. Results of quantitative analysis showed good correlation between ultrasound and pathology findings in 79.7% of cases (insufficient in 20.3%). However, if ultrasonography is combined with other ultrasound methods of examination (standard Doppler and spectral analysis of Doppler) correlation is of the order of 95%, close to morphological data supplied by arteriography, with in addition a functional and qualitative approach not possible with arteriography alone.

摘要

对1981年12月至1983年4月期间接受59次颈动脉内膜切除术的49例患者的超声、动脉造影和病理学检查结果进行了比较。通过颈部多普勒、高分辨率快速超声以及直接或更常用的静脉动脉造影(带摄影减法)对颈动脉病变进行常规检查。对术后内膜切除术标本进行检查,以确定狭窄的精确程度,并进行定性分析(溃疡和血栓形成的大体病理学和组织学、斑块的生化性质等)。关于检测,即证明动脉粥样硬化病变的存在与否,超声检查结果总能(100%的病例)与病理学数据相关。动脉粥样硬化病变的定性分析表明,某些病变很容易诊断:钙化、纤维或软骨样及脂质斑块,而那些合并出血、溃疡或壁内血栓形成的病变通过超声成像诊断的准确性较低。闭塞性斑块很容易检测到,而近期腔内血栓形成仅靠超声更难诊断。在这种情况下,多普勒的联合使用是一种有价值的辅助手段,实际上在该科室是一种常规操作。定量分析结果显示,79.7%的病例中超声与病理学检查结果具有良好的相关性(20.3%的病例相关性不足)。然而,如果将超声检查与其他超声检查方法(标准多普勒和多普勒频谱分析)相结合,相关性约为95%,接近动脉造影提供的形态学数据,此外还提供了单独动脉造影无法实现的功能和定性方法。

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