Chetvertkov Mikhail, Monroe James Ira, Boparai Jaskaran, Solberg Timothy D, Pafundi Deanna H, Ruo Russell L, Gladstone David J, Yin Fang-Fang, Chetty Indrin J, Benedict Stanley, Followill David S, Xiao Ying, Sohn Jason W
Cancer Institute, Allegheny Health Network, Pittsburgh, PA, United States.
Department of Radiation Oncology, Mercy Hospital South, St. Louis, MO, United States.
Front Oncol. 2020 Nov 27;10:602607. doi: 10.3389/fonc.2020.602607. eCollection 2020.
To assess stereotactic radiotherapy (SRT)/stereotactic body radiotherapy (SBRT) practices by polling clinics participating in multi-institutional clinical trials.
The NRG Oncology Medical Physics Subcommittee distributed a survey consisting of 23 questions, which covered general technologies, policies, and procedures used in the Radiation Oncology field for the delivery of SRT/SBRT (9 questions), and site-specific questions for brain SRT, lung SBRT, and prostate SBRT (14 questions). Surveys were distributed to 1,996 radiotherapy institutions included on the membership rosters of the five National Clinical Trials Network (NCTN) groups. Patient setup, motion management, target localization, prescriptions, and treatment delivery technique data were reported back by 568 institutions (28%).
97.5% of respondents treat lung SBRT patients, 77.0% perform brain SRT, and 29.1% deliver prostate SBRT. 48.8% of clinics require a physicist present for every fraction of SBRT, 18.5% require a physicist present for the initial SBRT fraction only, and 14.9% require a physicist present for the entire first fraction, including set-up approval for all subsequent fractions. 55.3% require physician approval for all fractions, and 86.7% do not reposition without x-ray imaging. For brain SRT, most institutions (83.9%) use a planning target volume (PTV) margin of 2 mm or less. Lung SBRT PTV margins of 3 mm or more are used in 80.6% of clinics. Volumetric modulated arc therapy (VMAT) is the dominant delivery method in 62.8% of SRT treatments, 70.9% of lung SBRT, and 68.3% of prostate SBRT.
This report characterizes SRT/SBRT practices in radiotherapy clinics participating in clinical trials. Data made available here allows the radiotherapy community to compare their practice with that of other clinics, determine what is achievable, and assess areas for improvement.
通过对参与多机构临床试验的诊所进行调查,评估立体定向放射治疗(SRT)/立体定向体部放射治疗(SBRT)的实践情况。
NRG肿瘤学医学物理小组委员会分发了一份包含23个问题的调查问卷,内容涵盖放射肿瘤学领域用于实施SRT/SBRT的一般技术、政策和程序(9个问题),以及针对脑部SRT、肺部SBRT和前列腺SBRT的特定部位问题(14个问题)。调查问卷分发给了五个国家临床试验网络(NCTN)组会员名单上的1996家放射治疗机构。568家机构(28%)反馈了患者摆位、运动管理、靶区定位、处方和治疗实施技术数据。
97.5%的受访者治疗肺部SBRT患者,77.0%进行脑部SRT,29.1%实施前列腺SBRT。48.8%的诊所要求每次SBRT治疗都有物理师在场,18.5%仅要求在首次SBRT治疗时有物理师在场,14.9%要求在整个首次治疗过程中都有物理师在场,包括对所有后续分次治疗的摆位核准。55.3%要求所有分次治疗都需医生批准,86.7%在没有X光成像的情况下不重新摆位。对于脑部SRT,大多数机构(83.9%)使用的计划靶区体积(PTV)边界为2毫米或更小。80.6%的诊所对肺部SBRT使用3毫米或更大的PTV边界。容积调强弧形放疗(VMAT)是62.8%的SRT治疗、70.9%的肺部SBRT和68.3%的前列腺SBRT的主要实施方法。
本报告描述了参与临床试验的放射治疗诊所的SRT/SBRT实践情况。此处提供的数据使放射治疗界能够将自己的实践与其他诊所进行比较,确定可实现的目标,并评估改进领域。