Krishnaswamy Amar, Kapadia Samir R
Department of Interventional Cardiology, Cleveland Clinic, Cleveland, OH, United States.
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, United States.
Front Cardiovasc Med. 2020 Nov 20;7:576058. doi: 10.3389/fcvm.2020.576058. eCollection 2020.
Patients with functional, or secondary, mitral regurgitation (FMR, SMR) often face significant symptoms that lead to functional decline as well as hospitalization and even death. Traditional mitral annuloplasty is an important treatment option for patients with FMR, but surgical risk and durability are important limitations. Percutaneous strategies are therefore a welcome alternative. The Carillon device utilizes the relationship of the coronary sinus and the mitral annulus to effect an "indirect" annuloplasty. Early series' and recent randomized trials suggest echocardiographic and clinical benefit with a relatively straight-forward implantation technique and low rate of significant complications.
功能性或继发性二尖瓣反流(FMR,SMR)患者常常面临严重症状,这些症状会导致功能下降、住院甚至死亡。传统二尖瓣环成形术是FMR患者的重要治疗选择,但手术风险和耐久性是重要局限。因此,经皮治疗策略是一种受欢迎的替代方法。Carillon装置利用冠状窦与二尖瓣环的关系来实现“间接”瓣环成形术。早期系列研究和近期随机试验表明,该技术具有相对简单的植入方法、显著并发症发生率低等特点,在超声心动图和临床方面均有获益。