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肺动脉起源异常的左冠状动脉修复结果:术前二尖瓣反流在随访中持续存在。

Anomalous left coronary artery from the pulmonary artery repair outcomes: Preoperative mitral regurgitation persists in the follow-up.

作者信息

Biçer Mehmet, Korun Oktay, Yurdakök Okan, Çiçek Murat, Dedemoğlu Mehmet, Özdemir Fatih, Kılıç Yiğit, Altın Hüsnü F, Şaşmazel Ahmet, Aydemir Numan A

机构信息

Pediatric Cardiovascular Surgery Department, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Pediatric Cardiovascular Surgery Department, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

出版信息

J Card Surg. 2021 Feb;36(2):530-535. doi: 10.1111/jocs.15247. Epub 2020 Dec 16.

Abstract

OBJECTIVE

This study aims to present the midterm outcomes of surgical correction of the anomalous left coronary artery from the pulmonary artery (ALCAPA) with a focus on mitral regurgitation (MR).

METHODS

Medical records of 36 ALCAPA patients who underwent surgery in a single center were retrospectively reviewed.

RESULTS

There were one (2.7%) neonate, 19 (52.7%) infants, 15 (41.6%) children, and 1 (2.7%) adult patient operated. Coronary reimplantation, tube reconstruction, and coronary artery bypass surgery techniques were performed in 29 (80.5%), 6 (16.6%), and 1 (2.7%) patient, respectively. Sixteen (44.4%) patients had a low ejection fraction and 13 (36.1%) patients had at least moderate MR preoperatively. None of our patients underwent a concomitant mitral surgery during the initial repair. Three and two patients died in the early and late postoperative period, respectively. Two patients underwent reoperation due to MR and pulmonary stenosis, separately. Preoperative MR was the only factor associated with at least moderate MR at the final follow-up (p < .01) and the presence of preoperative moderate or over-moderate MR estimated at least moderate MR at the final follow-up with 100% sensitivity and 80% specificity.

CONCLUSION

Although the mitral valve was not repaired in the first operation, the reoperation rate is low. However, a moderate or higher preoperative MR predicted MR at the last follow-up. Performing annuloplasty in such patients can be a strategy to be researched.

摘要

目的

本研究旨在呈现肺动脉起源异常左冠状动脉(ALCAPA)手术矫正的中期结果,重点关注二尖瓣反流(MR)。

方法

回顾性分析在单一中心接受手术的36例ALCAPA患者的病历。

结果

接受手术的患者中有1例(2.7%)新生儿、19例(52.7%)婴儿、15例(41.6%)儿童和1例(2.7%)成人。分别有29例(80.5%)、6例(16.6%)和1例(2.7%)患者采用了冠状动脉再植入、管道重建和冠状动脉搭桥手术技术。16例(44.4%)患者术前射血分数较低,13例(36.1%)患者术前至少有中度MR。我们的患者在初次修复期间均未同时进行二尖瓣手术。分别有3例和2例患者在术后早期和晚期死亡。2例患者分别因MR和肺动脉狭窄接受了再次手术。术前MR是与最终随访时至少中度MR相关的唯一因素(p < .01),术前中度或重度MR的存在以100%的敏感性和80%的特异性预测最终随访时至少中度MR。

结论

尽管首次手术未修复二尖瓣,但再次手术率较低。然而,术前中度或更高程度的MR可预测末次随访时的MR。对此类患者进行瓣环成形术可能是一种值得研究的策略。

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