Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia, São Paulo, SP, Brasil.
Universidade Federal de Santa Catarina, Faculdade de Medicina, Departamento de Clínica Médica, Florianópolis, SC, Brasil.
Arq Gastroenterol. 2020 Oct-Dec;57(4):381-398. doi: 10.1590/S0004-2803.202000000-72.
Over the last years, there is growing evidence that microorganisms are involved in the maintenance of our health and are related to various diseases, both intestinal and extraintestinal. Changes in the gut microbiota appears to be a key element in the pathogenesis of hepatic and gastrointestinal disorders, including non-alcoholic fatty liver disease, alcoholic liver disease, liver cirrhosis, inflammatory bowel disease, irritable bowel syndrome, and Clostridium difficile - associated diarrhea. In 2019, the Brazilian Society of Hepatology (SBH) in cooperation with the Brazilian Nucleus for the Study of Helicobacter Pylori and Microbiota (NBEHPM), and Brazilian Federation of Gastroenterology (FBG) sponsored a joint meeting on gut microbiota and the use of prebiotics, probiotics, and synbiotics in gastrointestinal and liver diseases. This paper summarizes the proceedings of the aforementioned meeting. It is intended to provide practical information about this topic, addressing the latest discoveries and indicating areas for future studies.
近年来,越来越多的证据表明微生物参与了我们的健康维持,并与各种疾病有关,包括肠道和肠道外疾病。肠道微生物群的变化似乎是肝和胃肠道疾病发病机制中的一个关键因素,包括非酒精性脂肪性肝病、酒精性肝病、肝硬化、炎症性肠病、肠易激综合征和艰难梭菌相关性腹泻。2019 年,巴西肝病学会(SBH)与巴西幽门螺杆菌和微生物组研究中心(NBEHPM)以及巴西胃肠病学联合会(FBG)合作,举办了一次关于肠道微生物群以及在胃肠道和肝脏疾病中使用益生元、益生菌和合生菌的联合会议。本文总结了上述会议的会议记录。其旨在提供有关该主题的实用信息,涉及最新发现,并指出未来研究的领域。