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出生后六小时内确定可能存在垂直传播。

Probable vertical transmission identified within six hours of life.

作者信息

Pessoa Fabrício Silva, Vale Marynéa Silva do, Marques Patrícia Franco, Figueira Susana da Silva, Salgado Izabel Athayde da Silva Cruz, Mochel Roberta de Sousa Wernz Cancian

机构信息

Infectologista Pediátrico. Serviço de Infectologia Pediátrica do Hospital Universitário da Universidade Federal do Maranhão, São Luis, MA, Brasil.

Neonatologista. Unidade de Cuidados Intensivos Perinatais do Hospital Universitário da Universidade Federal do Maranhão, São Luis, MA, Brasil.

出版信息

Rev Assoc Med Bras (1992). 2020 Dec;66(12):1621-1624. doi: 10.1590/1806-9282.66.12.1621.

DOI:10.1590/1806-9282.66.12.1621
PMID:33331566
Abstract

We present the case of 33 weeks + weeks pregnant patient (G1P0), with proven COVID-19 infection by RT-PCR and, at admission, she presented with a dry cough and "tiredness when talking,". Chest computed tomography was performed, which showed the presence of attenuations with ground glass opacification and bilateral consolidations. She then had a cesarean section because of maternal respiratory decompensation. She was transferred to the ICU of the same hospital with an O2 catheter. The newborn was transferred to the neonatal ICU of the same hospital in ambient air and maintained in respiratory and contact isolation. RT-PCR was collected for SARS-COV-2 at 6 h of life, which was positive. Faced with the knowledge gap on vertical transmission, RT-PCR for SARS-COV-2 at 6 h of life gives cause for concern, thus representing the possibility of vertical transmission by SARS-COV-2, although additional investigations are required.

摘要

我们报告一例33周+孕周的孕妇(G1P0),经逆转录聚合酶链反应(RT-PCR)证实感染了新冠病毒(COVID-19),入院时表现为干咳和“说话时感到疲倦”。进行了胸部计算机断层扫描,结果显示存在磨玻璃样混浊和双侧实变的低密度影。随后,由于产妇呼吸代偿失调,她接受了剖宫产手术。她通过氧气导管被转至同一家医院的重症监护病房(ICU)。新生儿在环境空气中被转至同一家医院的新生儿重症监护病房,并保持呼吸道和接触隔离。在出生后6小时采集了用于检测严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的RT-PCR样本,结果呈阳性。鉴于垂直传播方面的知识空白,出生后6小时的SARS-CoV-2 RT-PCR检测结果令人担忧,这表明存在SARS-CoV-2垂直传播的可能性,不过还需要进一步调查。

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引用本文的文献

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Is There an Effect of Fetal Mesenchymal Stem Cells in the Mother-Fetus Dyad in COVID-19 Pregnancies and Vertical Transmission?胎儿间充质干细胞对新冠病毒感染孕妇母婴二元组及垂直传播有影响吗?
Front Physiol. 2021 Feb 11;11:624625. doi: 10.3389/fphys.2020.624625. eCollection 2020.