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可能存在 COVID-19 经感染孕妇垂直传播给新生儿的早期病例报告。

Possible Early Vertical Transmission of COVID-19 from an Infected Pregnant Female to Her Neonate: A Case Report.

机构信息

Department of Neonatology, ABVIMS and Dr. RML Hospital, New Delhi 110001, India.

出版信息

J Trop Pediatr. 2021 Jan 29;67(1). doi: 10.1093/tropej/fmaa094.

DOI:10.1093/tropej/fmaa094
PMID:33221859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7717437/
Abstract

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-19) has emerged as a public health emergency in recent times. The reported data on the mode of transmission of coronavirus disease 2019 (COVID-19) are largely through contact, droplet, airborne and fomite transmission methods with vertical transmission being a rare entity. We hereby report a case of a probable vertical transmission of SARS-CoV-19 from an infected pregnant female to her neonate. The transmission has been confirmed by a positive RT-PCR at 16 h of life along with a positive IgG antibody test for SARS-CoV-19 in the baby and after excluding the possible environmental contamination of the sample. The baby was asymptomatic during the course of hospital stay and was discharged from the facility on Day 9 of life.

摘要

严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)已成为当前的公共卫生紧急事件。关于 2019 年冠状病毒病(COVID-19)传播方式的报告数据主要通过接触、飞沫、空气传播和接触传播方式,垂直传播是一种罕见的传播方式。在此,我们报告了一例可能由感染孕妇垂直传播 SARS-CoV-19 给她的新生儿的病例。通过对婴儿在 16 小时时的阳性 RT-PCR 检测,以及 SARS-CoV-19 的阳性 IgG 抗体检测,结合排除样本可能受到环境污染的情况,证实了这一传播。在住院期间,婴儿无症状,并于出生后第 9 天出院。

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