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经 tDCS 和计算机辅助认知训练后改善后部皮质萎缩患者的视觉空间忽视:一项单病例研究。

Improved visuospatial neglect after tDCS and computer-assisted cognitive training in Posterior Cortical Atrophy: a single-case study.

机构信息

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Department of Naval, Electric, Electronic and Telecommunications Engineering (DITEN), University of Genoa, Genoa, Italy.

出版信息

Neurocase. 2021 Feb;27(1):57-63. doi: 10.1080/13554794.2020.1862242. Epub 2020 Dec 17.

DOI:10.1080/13554794.2020.1862242
PMID:33332244
Abstract

Visuospatial neglect (VN) frequently occurs in Posterior Cortical Atrophy (PCA) and requires specific rehabilitation. In this single-case study, we investigated the efficacy of a computer-assisted cognitive training (CCT) alone or coupled with multiple sessions of anodal transcranial direct-current stimulation (A-tDCS) over the right posterior parietal cortex in improving left VN symptoms in a patient with PCA. The digital ReMoVES platform was used for both VN assessment and training. We found a significant improvement after CCT combined with A-tDCS within the limits of a single-case, our results suggest, for the first time, the usefulness of this combined approach in a neurodegenerative disorder.

摘要

视觉空间忽略(VN)在后部皮质萎缩(PCA)中经常发生,需要特定的康复治疗。在这项单病例研究中,我们研究了计算机辅助认知训练(CCT)单独或与多个右侧顶后区经颅直流电刺激(A-tDCS)联合应用对改善 PCA 患者左 VN 症状的疗效。数字 ReMoVES 平台用于 VN 评估和训练。我们在单病例范围内发现 CCT 联合 A-tDCS 后有显著改善,我们的结果首次表明,这种联合方法在神经退行性疾病中的有效性。

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