Sukovatykh B S, Sukovatykh M B, Polianskiĭ D V
Kursk State Medical University of the RF Ministry of Public Health, Kursk, Russia.
Angiol Sosud Khir. 2020;26(4):43-48. doi: 10.33529/ANGIO2020426.
The purpose of the present study was to investigate the dynamics of quality of life in patients with ischaemic heart disease before and after implantation of a coronary stent depending on the stent's type and patient's gender. The authors analysed the dynamics of quality of life in a total of 120 patients with ischaemic heart disease. The patients were subdivided into two equal groups of 60 each. Group One patients were subjected to implantation of bare-metal stents, whereas Group Two patients received stents coated with zotarolimus as an antiproliferative agent. The control group was composed of 60 people who did not suffer from ischaemic heart disease and were comparable by the age and gender. Quality of life was investigated prior to stent implantation and 6, 12 and 24 months thereafter with the use of the SF-36 questionnaire. It was determined that the indices of quality of life before stenting of coronary arteries was higher in men than in women. However, no gender-related differences were revealed after stent implantation. The dynamics of the parameters of quality of life of patients following implantation of uncoated metal stents within 6 months turned out to have a positive and then rapidly progressing negative course, whereas implantation of stents coated with antiproliferative drug zotarolimus was within 12 months followed and accompanied by a positive and then slowly progressing negative course.
本研究的目的是根据冠状动脉支架类型和患者性别，调查缺血性心脏病患者在植入冠状动脉支架前后的生活质量动态变化。作者分析了总共120例缺血性心脏病患者的生活质量动态变化。患者被平均分为两组，每组60人。第一组患者接受裸金属支架植入，而第二组患者接受涂有抗增殖药物佐他莫司的支架植入。对照组由60名未患缺血性心脏病且在年龄和性别上具有可比性的人组成。在支架植入前以及植入后6、12和24个月，使用SF-36问卷对生活质量进行调查。结果发现，冠状动脉支架植入前男性的生活质量指数高于女性。然而，支架植入后未发现与性别相关的差异。未涂层金属支架植入后6个月内患者生活质量参数的动态变化呈先正后迅速恶化的趋势，而植入涂有抗增殖药物佐他莫司的支架后12个月内，生活质量呈先正后缓慢恶化的趋势。
