Institut Cochin, CNRS, INSERM, Université de Paris, Paris, France.
Institut de Recherches SERVIER, Croissy-sur-Seine, France.
J Pineal Res. 2021 Mar;70(2):e12712. doi: 10.1111/jpi.12712. Epub 2021 Jan 5.
A multitude of effects has been attributed to melatonin at pmol/L to mmol/L concentrations. More than fifteen targets have been proposed for melatonin but only few of them are well characterized. The current guidelines intend to provide a framework to improve and rationalize the characterization of melatonin targets and effects. They should be considered as mandatory guidelines and minimum requirements for manuscripts submitted to the Journal of Pineal Research.
褪黑素在皮摩尔/升至毫摩尔/升浓度下具有多种作用。褪黑素已经提出了超过 15 个作用靶点，但其中只有少数得到了很好的描述。目前的指南旨在提供一个框架，以改善和合理化褪黑素作用靶点和作用的描述。这些指南应被视为提交给《松果体研究杂志》的稿件的强制性指南和最低要求。
