Transplant Institute, Loma Linda University Health, Loma Linda, California, USA.
Curr Opin Organ Transplant. 2021 Feb 1;26(1):62-68. doi: 10.1097/MOT.0000000000000843.
Kidney and/or pancreas transplantation candidacy criteria have evolved significantly over time reflecting improved pre and post-transplant management. With improvement in medical care, potential candidates for transplant not only are older but also have complex medical issues. This review focuses on the latest trends regarding candidacy for kidney and/or pancreas transplantation along with advances in pretransplant cardiac testing.
More candidates are now eligible for kidney and/or pancreas transplantation owing to less stringent candidacy criteria especially in regards to age, obesity, frailty and history of prior malignancy. Pretransplant cardiovascular assessment has also come a long way with a focus on less invasive strategies to assess for coronary artery disease.
Criteria for kidney and/or pancreas transplantation are expanding. Patients who in the past might have been declined because of numerous factors are now finding that transplant centers are more open minded to their candidacy, which could lead to better access to organ transplant wait list.
随着肾和/或胰移植术前及术后管理水平的提高，肾和/或胰移植候选者的标准也发生了显著的变化。随着医疗水平的提高，接受移植的潜在候选者不仅年龄更大，而且还存在复杂的医疗问题。本综述重点关注肾和/或胰移植候选者的最新趋势，以及移植前心脏检查的进展。
由于候选者标准放宽，特别是在年龄、肥胖、虚弱和既往恶性肿瘤病史方面，现在有更多的候选者有资格接受肾和/或胰移植。移植前心血管评估也取得了很大的进展，重点是采用创伤更小的策略来评估冠状动脉疾病。
肾和/或胰移植的标准正在放宽。过去因多种因素而被拒绝的患者，现在发现移植中心对他们的候选资格更加开放，这可能会使他们更容易获得器官移植等待名单。
