Spine Center, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Department of Orthopaedic Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
World Neurosurg. 2021 Mar;147:e315-e323. doi: 10.1016/j.wneu.2020.12.044. Epub 2020 Dec 15.
Proximal junctional kyphosis (PJK) is a common sagittal complication of adolescent idiopathic scoliosis (AIS) after corrective surgery, leading to new deformities, pain, and, even, revision surgery. In the present study, we investigated the risk and predictive factors for PJK in patients who had undergone Lenke type 5 AIS correction to identify the parameters relevant to intraoperative guidance.
A total of 35 patients with Lenke type 5 AIS who had undergone corrective surgery at our hospital from January 2008 to February 2016 were divided into the PJK (n = 15) and non-PJK (n = 20) groups. Correlation and receiver operating characteristic curve analyses were performed to screen the parameters for significance and calculate the thresholds. A survival analysis was performed to examine the differences between the 2 groups.
Independent t tests revealed significant differences between the 2 groups in the preoperative pelvic incidence, preoperative pelvic tilt, postoperative proximal junctional angle (PJA), and postoperative thoracic kyphosis (TK). The postoperative PJA, postoperative TK, and other parameters correlated significantly with changes in the PJA at the final follow-up. The receiver operating characteristic curves revealed that the postoperative PJA and postoperative TK effectively predicted for the occurrence of PJK, with a threshold of 9.45° and 25.25°, respectively. The estimated survival times were 14.7 months for a PJA >9.45° and TK >25.25°, 19.2 months for a PJA >9.45°, and 33.9 months for TK >25.25°.
The results of the present study have shown that the postoperative PJA and postoperative TK can be used to effectively predict for the occurrence of PJK in patients with Lenke type 5 AIS after corrective surgery, with a threshold of 9.45° and 25.25°, respectively.
近端交界性后凸(PJK)是青少年特发性脊柱侧凸(AIS)矫形手术后常见的矢状面并发症,可导致新的畸形、疼痛,甚至需要翻修手术。本研究旨在探讨 Lenke 型 5 度 AIS 矫正术后 PJK 的风险和预测因素,以确定与术中指导相关的参数。
回顾性分析 2008 年 1 月至 2016 年 2 月在我院接受 Lenke 型 5 度 AIS 矫正手术的 35 例患者,根据术后是否发生 PJK 分为 PJK 组(n=15)和非 PJK 组(n=20)。采用相关性分析和受试者工作特征曲线分析筛选有意义的参数并计算阈值。采用生存分析比较两组患者的差异。
两组患者术前骨盆入射角、骨盆倾斜角、术后近端交界角(PJA)和术后胸椎后凸(TK)比较,差异有统计学意义(P<0.05)。术后 PJA、术后 TK 及其他参数与末次随访时 PJA 的变化显著相关。受试者工作特征曲线显示,术后 PJA 和术后 TK 可有效预测 PJK 的发生,阈值分别为 9.45°和 25.25°。PJA>9.45°且 TK>25.25°时,估计的生存时间为 14.7 个月;PJA>9.45°时,估计的生存时间为 19.2 个月;TK>25.25°时,估计的生存时间为 33.9 个月。
本研究结果表明,术后 PJA 和术后 TK 可有效预测 Lenke 型 5 度 AIS 矫正术后 PJK 的发生,阈值分别为 9.45°和 25.25°。