Department of Surgery, Division of Trauma, Critical Care, Burn and Acute Care Surgery, MetroHealth Medical Center, OH, USA.
School of Medicine, Case Western Reserve University, OH, USA.
Am Surg. 2021 Jul;87(7):1118-1125. doi: 10.1177/0003134820952387. Epub 2020 Dec 17.
We sought to evaluate risk factors for wound infection in patients with lower extremity (LE) burn.
Adults presenting with LE burn from January 2014 to July 2015 were included. Data regarding demographics, injury characteristics, and outcomes were obtained. The primary outcome was wound infection. Multivariate logistic regression analysis was performed to identify independent risk factors for wound infection.
317 patients were included with a mean age of 43 years and median total body surface area of .8%; 22 (7%) patients had a component of full-thickness (FT) burn; and 212 (67%) patients had below-the-knee (BTK) burn. The incidence of wound infection was 15%. The median time to infection was 5 days, and majority (61%) of the patients developed wound infection by day 5. Patients who developed wound infection were more likely to have an FT burn (22% vs. 5%, < .001) and BTK burn (87% vs. 64%, = .002), without a difference in other variables. Multivariate logistic regression analysis showed age (Odds ratio (OR) 1.02 and CI 1.00-1.04), presence of FT burn (OR 5.33 and CI 2.09-13.62), and BTK burn (OR 3.42 and CI 1.37-8.52) as independent risk factors for wound infection (area under the curve = .72).
Age, presence of FT burn, and BTK burn are independent risk factors for wound infection in outpatients with LE burns.
我们旨在评估下肢烧伤患者伤口感染的危险因素。
纳入 2014 年 1 月至 2015 年 7 月就诊的下肢烧伤成人患者。收集人口统计学、损伤特征和结局数据。主要结局为伤口感染。采用多变量 logistic 回归分析确定伤口感染的独立危险因素。
共纳入 317 例患者，平均年龄 43 岁，中位数总体表面积为 8%；22 例（7%）患者有全层（FT）烧伤成分；212 例（67%）患者有膝下（BTK）烧伤。伤口感染发生率为 15%。感染的中位时间为 5 天，大多数（61%）患者在第 5 天发生伤口感染。发生伤口感染的患者更可能有 FT 烧伤（22% vs. 5%， <.001）和 BTK 烧伤（87% vs. 64%， =.002），其他变量无差异。多变量 logistic 回归分析显示，年龄（优势比（OR）1.02，95%置信区间（CI）1.00-1.04）、FT 烧伤（OR 5.33，95%CI 2.09-13.62）和 BTK 烧伤（OR 3.42，95%CI 1.37-8.52）是伤口感染的独立危险因素（曲线下面积=.72）。
年龄、FT 烧伤和 BTK 烧伤是下肢烧伤门诊患者伤口感染的独立危险因素。
