肥胖对 COVID-19 的细胞和分子病理生理学的影响。
The impact of obesity on the cellular and molecular pathophysiology of COVID-19.
机构信息
Department of Immunology, Institute for Cellular and Molecular Medicine, SAMRC Extramural Unit for Stem Cell Research and Therapy, Faculty of Health Sciences, University of Pretoria, South Africa.
出版信息
S Afr Med J. 2020 Dec 14;0(0):13184.
Emerging evidence reveals a strong association between COVID-19 and obesity in terms of disease severity, need for hospitalisation and risk of mortality. In this review, we discuss cellular and molecular mechanisms potentially contributing to the pathophysiology of COVID-19 in obese patients. Understanding the relationship between COVID-19 and obesity is pertinent for the clinical management of these patients.
新出现的证据表明，COVID-19 与肥胖症在疾病严重程度、住院需求和死亡率方面存在很强的关联。在这篇综述中，我们讨论了可能导致肥胖患者 COVID-19 病理生理学的细胞和分子机制。了解 COVID-19 与肥胖症之间的关系对于这些患者的临床管理具有重要意义。
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