恢复抗体相关的迟发性无视网膜病性共济失调。
Recoverin antibody-associated late-onset ataxia without retinopathy.
机构信息
Department of Neurology, Universitätsklinikum Schleswig-Holstein Campus Lübeck Klinik für Neurologie, Lubeck, Schleswig-Holstein, Germany
Institute of Systems Motor Science, Universität zu Lübeck, Lubeck, Schleswig-Holstein, Germany.
出版信息
BMJ Case Rep. 2020 Dec 17;13(12):e237479. doi: 10.1136/bcr-2020-237479.
Abstract
Acquired cerebellar ataxia is a rare, in many cases immune-modulated and paraneoplastic illness. Acute and slowly progredient processes are possible. An early treatment is important for a good clinical outcome. Here we present the case of female patient in her 60s with an antirecoverin associated cerebellitis without retinopathia and neoplasia. After an immunosuppressive therapy with steroids and rituximab the symptoms improved, and the progression could be stopped.
摘要
获得性小脑共济失调是一种罕见的疾病，在许多情况下与免疫调节和副肿瘤有关。可能会出现急性和缓慢进展的过程。早期治疗对于良好的临床预后非常重要。在此，我们报告了一例 60 多岁的女性患者，患有抗富亮氨酸胶质瘤失活 1 蛋白相关小脑炎，无视网膜病和肿瘤。经类固醇和利妥昔单抗免疫抑制治疗后，症状改善，病情进展得到控制。
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