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第一民族高中人群阿片类药物使用障碍的长期治疗结果。

Long-term treatment outcomes in a First Nations high school population with opioid use disorder.

机构信息

Associate Professor and Family and Addiction Medicine physician at Women's College Hospital and St Joseph's Health Centre in the Department of Community and Family Medicine at the University of Toronto in Ontario.

Medical Director of the Substance Use Service at Women's College Hospital and Associate Professor in the Department of Family and Community Medicine at the University of Toronto.

出版信息

Can Fam Physician. 2020 Dec;66(12):907-912. doi: 10.46747/cfp.6612907.

Abstract

OBJECTIVE

To assess for long-term positive effects of buprenorphine treatment (BT) on opioid use disorder (OUD) at a Nishnawbe Aski Nation high school clinic.

DESIGN

Postgraduation telephone survey of high school students between March 2017 and January 2018.

SETTING

Dennis Franklin Cromarty High School in Thunder Bay, Ont.

PARTICIPANTS

All 44 students who had received BT in the high school clinic during its operation from 2011 to 2013 were eligible to participate.

MAIN OUTCOME MEASURES

Current substance use, BT status, and social and employment status.

RESULTS

Thirty-eight of the 44 students who had received BT in the high school clinic were located and approached; 32 consented to participate in the survey. A descriptive analysis of the surveyed indicators was undertaken. Almost two-thirds (n = 20, 62.5%) of the cohort had graduated from high school, more than one-third (n = 12, 37.5%) were employed full time, and most (n = 29, 90.6%) rated their health as "good" or "OK." A greater percentage of participants who continued taking BT after high school (n = 19, 61.3%) were employed full time (n = 8, 42.1% vs n = 4, 33.3%) and were abstinent from alcohol (n = 12, 63.2% vs n = 4, 33.3%). Participants still taking BT were significantly more likely to have obtained addiction counseling in the past year than those participants not in treatment (n = 9, 47.4% vs n = 1, 8.3%; = .0464).

CONCLUSION

The study results suggest that offering OUD treatment to youth in the form of BT in a high school clinic might be an effective strategy for promoting positive long-term health and social outcomes. Clinical treatment guidelines currently recommend long-term opioid agonist treatment as the treatment of choice for OUD in the general population; they should consider adding youth to the population that might also benefit.

摘要

目的

评估在努纳武特地区一所高中诊所进行丁丙诺啡治疗(BT)对阿片类药物使用障碍(OUD)的长期积极影响。

设计

2017 年 3 月至 2018 年 1 月期间,对高中毕业后的学生进行电话调查。

地点

安大略省桑德贝的丹尼斯·弗兰克林·克罗默蒂高中。

参与者

所有在 2011 年至 2013 年该高中诊所运营期间接受 BT 治疗的 44 名学生均符合参与条件。

主要观察指标

目前的物质使用情况、BT 状况以及社会和就业状况。

结果

在接受 BT 治疗的 44 名高中诊所学生中,有 38 名被找到并联系上;32 名同意参与调查。对调查指标进行了描述性分析。队列中有近三分之二(n = 20,62.5%)的人已经从高中毕业,超过三分之一(n = 12,37.5%)全职就业,大多数(n = 29,90.6%)认为自己的健康状况“良好”或“尚可”。在高中毕业后继续接受 BT 治疗的参与者中(n = 19,61.3%),有更多人全职就业(n = 8,42.1%比 n = 4,33.3%)且未饮酒(n = 12,63.2%比 n = 4,33.3%)。过去一年中,仍在接受 BT 治疗的参与者接受成瘾咨询的可能性明显高于未接受治疗的参与者(n = 9,47.4%比 n = 1,8.3%; =.0464)。

结论

研究结果表明,在高中诊所为青少年提供丁丙诺啡治疗(BT)可能是促进长期积极健康和社会结果的有效策略。目前的临床治疗指南建议,将长期阿片类药物激动剂治疗作为普通人群 OUD 的首选治疗方法;他们应该考虑将青少年纳入可能受益的人群。

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