永久性心房颤动患者粗F波与血栓栓塞事件之间的关系。
Relationship between coarse F waves and thromboembolic events in patients with permanent atrial fibrillation.
作者信息
İçen Yahya Kemal, Koca Hasan, Sümbül Hilmi Erdem, Yıldırım Arafat, Koca Fadime, Yıldırım Abdullah, Ardıc Mustafa Lutfullah, Coşkun Mükremin, Uğurlu Mehmet, Koç Mevlüt
机构信息
Department of Cardiology University of Health Sciences - Adana Health Practice and Research Center Adana Turkey.
Department of Internal Medicine University of Health Sciences - Adana Health Practice and Research Center Adana Turkey.
出版信息
J Arrhythm. 2020 Sep 2;36(6):1025-1031. doi: 10.1002/joa3.12430. eCollection 2020 Dec.
BACKGROUND
The coarse F waves on the 12-lead surface electrocardiogram (ECG) in patients with atrial fibrillation (AF) are known as atrial viability and contractility indicator. Our aim in this study was to investigate the effect of coarse F wave on thromboembolism in patients with permanent AF.
METHODS
In our study, 328 patients with permanent AF were included. Routine laboratory, echocardiographic and electrocardiographic parameters were examined. Cerebrovascular event (CVE) or acute artery occlusion was considered a thromboembolic event.
RESULTS
In our study, 46 (14.0%) of the patients were found to have thromboembolic events and 282 (86%) of them were found without thromboembolic events. In the group with thromboembolic event, the number of patients with hypertension (HT) ( < .001) and history of coronary artery disease ( = .003) and elderly patients ( < .001) was significantly higher and warfarin use was significantly lower ( = .025). In the group of patients without thromboembolic events, the number of patients with a coarse F wave in surface ECG was significantly lower ( = .001). Age (OR: 1.105, 95% CI: 1.066-1.145, < .001), HT (OR: 2.831, 95% CI: 1.266-6.331, = .011), and coarse F wave (OR: 0.290, 95% CI: 0.126- 0.670, = .004) were determined as independent variables for thromboembolic events.
CONCLUSION
Coarse F wave in 12-lead surface ECG in patients with permanent AF may be associated with good prognosis.
背景
心房颤动（AF）患者12导联体表心电图（ECG）上的粗F波被认为是心房存活性和收缩性指标。本研究的目的是探讨粗F波对永久性AF患者血栓栓塞的影响。
方法
本研究纳入328例永久性AF患者。检查常规实验室、超声心动图和心电图参数。脑血管事件（CVE）或急性动脉闭塞被视为血栓栓塞事件。
结果
本研究中，46例（14.0%）患者发生血栓栓塞事件，282例（86%）未发生血栓栓塞事件。在血栓栓塞事件组中，高血压（HT）患者数量（<0.001）、冠状动脉疾病史患者数量（=0.003）及老年患者数量（<0.001）显著更高，华法林使用显著更低（=0.025）。在无血栓栓塞事件的患者组中，体表心电图出现粗F波的患者数量显著更低（=0.001）。年龄（OR：1.105，95%CI：1.066-1.145，<0.001）、HT（OR：2.831，95%CI：1.266-6.331，=0.011）和粗F波（OR：0.290，95%CI：0.126-0.670，=0.004）被确定为血栓栓塞事件的独立变量。
结论
永久性AF患者12导联体表心电图上的粗F波可能与良好预后相关。
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