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低能量髋部骨折患者的维生素D水平

Vitamin D Levels in Patients with Low-energy Hip Fractures.

作者信息

Han Jaehwi, Cho Youngho, Jee Seungmin, Jo Seongwoo

机构信息

Department of Orthopaedic Surgery, Daegu Fatima Hospital, Daegu, Korea.

出版信息

Hip Pelvis. 2020 Dec;32(4):192-198. doi: 10.5371/hp.2020.32.4.192. Epub 2020 Dec 3.

DOI:10.5371/hp.2020.32.4.192
PMID:33335867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7724022/
Abstract

PURPOSE

To evaluate serum 25(OH) vitamin D levels in patients with low-energy hip fractures.

MATERIALS AND METHODS

Among 983 patients who underwent hip fracture surgery between August 2013 and March 2019, 732 patients were evaluated. The remaining patients were excluded due to the presence of one or more of the following: metastatic bone tumor, metabolic bone disease other than osteoporosis, fracture due to high-energy injury, atypical femoral fracture, and no blood test. We collected patient's data about age, sex male female, date of injury, a place of residence, fracture type, preinjury ambulation ability according to their Koval score, and their serum level of 25(OH) vitamin D. The mean age was 79.3 years (60-104 years). The sample was comprised of 530 female and 202 male, of which 342 had femoral neck fractures and 390 had trochanteric fractures.

RESULTS

Of the total 732 patients, 346 patients (47.3%) had a 25(OH) vitamin D level of less than 10 ng/mL, 264 patients (36.1%) had scores of 10-19.9 ng/mL, 87 patients (11.9%) had scores of 20-29.9 ng/mL, and 35 patients (4.8%) had a level higher than 30 ng/mL. Vitamin D deficiency (less than 20 ng/mL) was present in 610 patients (83.3%), insufficiency (20-29.9 ng/mL) was found in 87 patients (11.9%), and 35 patients (4.8%) had normal vitamin D levels. The differences in vitamin D concentration based on season and fracture type were statistically significant.

CONCLUSION

Vitamin D deficiency and inadequacy were high in patients with low-energy hip fractures, with only 4.9% of patients had normal vitamin D levels. These findings suggest that efforts should be made to maintain proper vitamin D concentration.

摘要

目的

评估低能量髋部骨折患者的血清25(OH)维生素D水平。

材料与方法

在2013年8月至2019年3月期间接受髋部骨折手术的983例患者中,对732例患者进行了评估。其余患者因存在以下一种或多种情况而被排除:转移性骨肿瘤、除骨质疏松症外的代谢性骨病、高能损伤导致的骨折、非典型股骨骨折以及未进行血液检查。我们收集了患者的年龄、性别(男/女)、受伤日期、居住地、骨折类型、根据Koval评分的伤前行走能力以及血清25(OH)维生素D水平等数据。平均年龄为79.3岁(60 - 104岁)。样本包括530名女性和202名男性,其中342例为股骨颈骨折,390例为转子间骨折。

结果

在总共732例患者中,346例患者(47.3%)的25(OH)维生素D水平低于10 ng/mL,264例患者(36.1%)的水平为10 - 19.9 ng/mL,87例患者(11.9%)的水平为20 - 29.9 ng/mL,35例患者(4.8%)的水平高于30 ng/mL。610例患者(83.3%)存在维生素D缺乏(低于20 ng/mL),87例患者(11.9%)存在不足(20 - 29.9 ng/mL),35例患者(4.8%)维生素D水平正常。基于季节和骨折类型的维生素D浓度差异具有统计学意义。

结论

低能量髋部骨折患者中维生素D缺乏和不足的情况很普遍,只有4.9%的患者维生素D水平正常。这些发现表明应努力维持适当的维生素D浓度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1877/7724022/6e421ae8f8d5/hp-32-192-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1877/7724022/241a5da2238b/hp-32-192-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1877/7724022/6e421ae8f8d5/hp-32-192-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1877/7724022/241a5da2238b/hp-32-192-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1877/7724022/6e421ae8f8d5/hp-32-192-g003.jpg

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Medicine (Baltimore). 2018 Jun;97(26):e11032. doi: 10.1097/MD.0000000000011032.
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Am J Clin Nutr. 2016 Apr;103(4):1033-44. doi: 10.3945/ajcn.115.120873. Epub 2016 Feb 10.
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Vitamin D Deficiency Is Highly Concomitant but Not Strong Risk Factor for Mortality in Patients Aged 50 Year and Older with Hip Fracture.
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Naïve Bayes is an interpretable and predictive machine learning algorithm in predicting osteoporotic hip fracture in-hospital mortality compared to other machine learning algorithms.与其他机器学习算法相比,朴素贝叶斯是一种可解释且具有预测性的机器学习算法,用于预测骨质疏松性髋部骨折患者的院内死亡率。
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[Sacral fragility fractures: risk factors and outcomes after cement sacroplasty].[骶骨脆性骨折:骨水泥骶骨成形术后的危险因素及预后]
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