阿司匹林加重性呼吸疾病相关性慢性鼻-鼻窦炎治疗中的嗅觉结果
Olfactory outcomes in the management of aspirin exacerbated respiratory disease related chronic rhinosinusitis.
作者信息
Spielman Daniel B, Overdevest Jonathan, Gudis David A
机构信息
Department of Otolaryngology - Head and Neck Surgery, Columbia University Medical Center, New York, NY, 10032, USA.
出版信息
World J Otorhinolaryngol Head Neck Surg. 2020 Aug 26;6(4):207-213. doi: 10.1016/j.wjorl.2020.07.001. eCollection 2020 Dec.
Abstract
Patients with aspirin exacerbated respiratory disease (AERD) experience a severe and recalcitrant form of chronic rhinosinusitis with nasal polyposis (CRSwNP) and asthma, which are exacerbated by aspirin/NSAID ingestion. As compared with aspirin-tolerant CRSwNP, patients with AERD experience more severe olfactory dysfunction, which is one of the key contributors to the observed decrease in quality of life (QOL) in this disease. The objective of this paper is to review the published olfactory outcomes observed with various treatment modalities.
摘要
阿司匹林加重性呼吸系统疾病（AERD）患者会经历一种严重且难治的慢性鼻-鼻窦炎伴鼻息肉（CRSwNP）和哮喘，阿司匹林/非甾体抗炎药（NSAID）的摄入会使病情加重。与阿司匹林耐受的CRSwNP患者相比，AERD患者存在更严重的嗅觉功能障碍，这是该疾病中观察到的生活质量（QOL）下降的关键因素之一。本文的目的是综述各种治疗方式下已发表的嗅觉相关结果。
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