• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

心室辅助装置中的湍流和湍流结构——使用大涡模拟的数值研究。

Turbulence and turbulent flow structures in a ventricular assist device-A numerical study using the large-eddy simulation.

机构信息

Faculty of Mechanical Engineering and Marine Technology, Institute of Turbomachinery, University of Rostock, Rostock, Germany.

出版信息

Int J Numer Method Biomed Eng. 2021 Mar;37(3):e3431. doi: 10.1002/cnm.3431. Epub 2021 Jan 31.

DOI:10.1002/cnm.3431
PMID:33336869
Abstract

Numerical flow simulations that analyze the turbulent flow characteristics within a turbopump are important for optimizing the efficiency of such machines. In the case of ventricular assist devices (VADs), turbulent flow characteristics must be also examined in order to improve hemocompatibility. Turbulence increases the shear stresses in the VAD flow, which can lead to an increased damage to the transported blood components. Therefore, an understanding of the turbulent flow patterns and their significance for the numerical blood damage prediction is particularly important for flow optimizations in VADs in order to identify and thus minimize flow regions where blood could be damaged due to high turbulent stresses. Nevertheless, the turbulence occurring in VADs and the local turbulent structures that lead to increased turbulent stresses have not yet been analyzed in detail in these machines. Therefore, this study aims to investigate the turbulence in an axial VAD in a comprehensive and double tracked way. First, the flow in an axial VAD was computed using the large-eddy simulation method, and it was verified that the majority of the turbulence was directly resolved by the simulation. Then, the turbulent flow state of the VAD was quantified globally. For this purpose, a self-designed evaluation method, the power loss analysis, was used. Subsequently, local flow regions and flow structures were identified where significant turbulent stresses prevail. It will be shown that the identified regions are universal and will also occur in other axial blood pumps as well, for example, in the HeartMate II.

摘要

数值流动模拟分析涡轮泵内的湍流特性对于优化此类机器的效率非常重要。在心室辅助装置(VAD)的情况下,为了提高血液相容性,也必须检查湍流特性。湍流会增加 VAD 流中的剪切应力,从而导致输送的血液成分增加损伤。因此,了解湍流流动模式及其对数值血液损伤预测的意义对于 VAD 中的流动优化尤为重要,以便识别并因此最小化由于高湍流应力而可能导致血液受损的流动区域。然而,在这些机器中,VAD 中的湍流和导致湍流应力增加的局部湍流结构尚未得到详细分析。因此,本研究旨在以全面和双跟踪的方式研究轴向 VAD 中的湍流。首先,使用大涡模拟方法计算了轴向 VAD 中的流动,并验证了模拟直接解析了大部分湍流。然后,全局量化了 VAD 的湍流流动状态。为此,使用了自行设计的评估方法,即功率损耗分析。随后,确定了存在显著湍流应力的局部流动区域和流动结构。结果表明,所确定的区域是普遍存在的,也会出现在其他轴向血液泵中,例如 HeartMate II。

相似文献

1
Turbulence and turbulent flow structures in a ventricular assist device-A numerical study using the large-eddy simulation.心室辅助装置中的湍流和湍流结构——使用大涡模拟的数值研究。
Int J Numer Method Biomed Eng. 2021 Mar;37(3):e3431. doi: 10.1002/cnm.3431. Epub 2021 Jan 31.
2
Influence of turbulent shear stresses on the numerical blood damage prediction in a ventricular assist device.湍流剪应力对心室辅助装置中血液损伤数值预测的影响。
Int J Artif Organs. 2019 Dec;42(12):735-747. doi: 10.1177/0391398819861395. Epub 2019 Jul 21.
3
Large eddy simulation in a rotary blood pump: Viscous shear stress computation and comparison with unsteady Reynolds-averaged Navier-Stokes simulation.旋转血泵中的大涡模拟:粘性剪切应力计算及与非定常雷诺平均纳维-斯托克斯模拟的比较
Int J Artif Organs. 2018 Nov;41(11):752-763. doi: 10.1177/0391398818777697. Epub 2018 Jun 13.
4
Large-Eddy Simulations of Flow in the FDA Benchmark Nozzle Geometry to Predict Hemolysis.用于预测溶血的美国食品药品监督管理局基准喷嘴几何形状内流动的大涡模拟
Cardiovasc Eng Technol. 2020 Jun;11(3):254-267. doi: 10.1007/s13239-020-00461-3. Epub 2020 Apr 15.
5
Multi-indicator analysis of mechanical blood damage with five clinical ventricular assist devices.五种临床心室辅助装置的血液机械损伤的多指标分析。
Comput Biol Med. 2022 Dec;151(Pt A):106271. doi: 10.1016/j.compbiomed.2022.106271. Epub 2022 Nov 5.
6
Thromboresistance comparison of the HeartMate II ventricular assist device with the device thrombogenicity emulation- optimized HeartAssist 5 VAD.HeartMate II心室辅助装置与模拟装置血栓形成性优化的HeartAssist 5心室辅助装置的抗血栓性比较。
J Biomech Eng. 2014 Feb;136(2):021014. doi: 10.1115/1.4026254.
7
The effect of turbulence on transitional flow in the FDA's benchmark nozzle model using large-eddy simulation.使用大涡模拟研究湍流对美国食品药品监督管理局基准喷嘴模型中过渡流的影响。
Int J Numer Method Biomed Eng. 2020 Oct;36(10):e3389. doi: 10.1002/cnm.3389. Epub 2020 Aug 27.
8
Computational characterization of flow and blood damage potential of the new maglev CH-VAD pump versus the HVAD and HeartMate II pumps.新型磁悬浮 CH-VAD 泵与 HVAD 和 HeartMate II 泵的血流和血液损伤潜力的计算特性。
Int J Artif Organs. 2020 Oct;43(10):653-662. doi: 10.1177/0391398820903734. Epub 2020 Feb 11.
9
Turbulent flow field in maglev centrifugal blood pumps of CH-VAD and HeartMate III: secondary flow and its effects on pump performance.CH-VAD和HeartMate III磁悬浮离心式血泵中的湍流流场:二次流及其对泵性能的影响。
Biomech Model Mechanobiol. 2024 Oct;23(5):1571-1589. doi: 10.1007/s10237-024-01855-1. Epub 2024 May 31.
10
Hemolysis Related to Turbulent Eddy Size Distributions Using Comparisons of Experiments to Computations.通过实验与计算的比较研究与湍流涡旋尺寸分布相关的溶血现象。
Artif Organs. 2015 Dec;39(12):E227-39. doi: 10.1111/aor.12572. Epub 2015 Sep 28.

引用本文的文献

1
An in silico analysis of heart rate impact on wall shear stress hemodynamic parameters in aortic coarctation.主动脉缩窄中心率对壁面切应力血流动力学参数影响的计算机模拟分析
Sci Rep. 2025 Jan 22;15(1):2747. doi: 10.1038/s41598-025-85522-0.
2
Dynamic VAD simulations: Performing accurate simulations of ventricular assist devices in interaction with the cardiovascular system.动态 VAD 模拟:在与心血管系统相互作用的情况下,对心室辅助装置进行精确模拟。
Int J Artif Organs. 2024 Aug;47(8):624-632. doi: 10.1177/03913988241268067. Epub 2024 Sep 5.
3
Enhancing the implantation of mechanical circulatory support devices using computational simulations.
利用计算模拟增强机械循环支持装置的植入效果。
Front Bioeng Biotechnol. 2024 Apr 25;12:1279268. doi: 10.3389/fbioe.2024.1279268. eCollection 2024.
4
Effect of Particle Migration on the Stress Field in Microfluidic Flows of Blood Analog Fluids at High Reynolds Numbers.高雷诺数下颗粒迁移对血液模拟流体微流场中应力场的影响。
Micromachines (Basel). 2023 Jul 25;14(8):1494. doi: 10.3390/mi14081494.
5
Fluid-structure interaction modelling of a positive-displacement Total Artificial Heart.容积式全人工心脏的流固耦合建模
Sci Rep. 2023 Apr 14;13(1):5734. doi: 10.1038/s41598-023-32141-2.
6
Flow simulation-based particle swarm optimization for developing improved hemolysis models.基于流动模拟的粒子群优化算法在改进溶血模型中的应用。
Biomech Model Mechanobiol. 2023 Apr;22(2):401-416. doi: 10.1007/s10237-022-01653-7. Epub 2022 Nov 28.