Suppr超能文献

电抽搐治疗超难治性癫痫持续状态的病例系列研究。

A case series of super-refractory status epilepticus successfully treated with electroconvulsive therapy.

机构信息

Neurology Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Department of Psychiatry, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

出版信息

Epileptic Disord. 2020 Dec 1;22(6):828-833. doi: 10.1684/epd.2020.1233.

Abstract

Super-refractory status epilepticus (SRSE) is a neurocritical emergency, associated with significant morbidity and mortality. The precise pathophysiology is still not completely understood. The likelihood of spontaneous seizure termination reduces with time, and it is of paramount importance to abort status in order to prevent permanent long-term neurological sequelae and death. A few neuroprotective strategies, such as general anaesthesia, steroids, ketogenic diet and hypothermia, have been used to treat SRSE, however, the clinical outcome remains inconclusive. We herein present two cases of SRSE, which were successfully treated with electroconvulsive therapy (ECT) after failing all pharmacological measures.

摘要

超难治性癫痫持续状态(SRSE)是一种神经危重症,与较高的发病率和死亡率相关。其确切的病理生理学机制仍不完全清楚。随着时间的推移,自发性癫痫终止的可能性降低,因此终止癫痫持续状态对于预防永久性长期神经后遗症和死亡至关重要。一些神经保护策略,如全身麻醉、类固醇、生酮饮食和低温,已被用于治疗 SRSE,但临床结果仍不确定。我们在此介绍两例 SRSE 患者,在所有药物治疗措施失败后,均成功地接受了电休克治疗(ECT)。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验