Shin Hye-Rim, Kim Minah, Park Kyung-Il
Department of Neurology, Dankook University Hospital, Cheonan, Korea.
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea.
Encephalitis. 2023 Oct;3(4):103-108. doi: 10.47936/encephalitis.2023.00059. Epub 2023 Jul 13.
Electroconvulsive therapy (ECT) is a widely used therapeutic option of drug-refractory psychiatric disorders. ECT treats psychiatric symptoms by inducing brief controlled seizures through electrical stimulation, but ECT does not generally cause prolonged seizures or epilepsy. However, several studies have reported cases of prolonged seizures after ECT. This review aimed to determine the mechanism of epileptogenesis with neurobiological changes after ECT. Contrary to epileptogenesis by ECT, several cases have reported that ECT was successfully applied for treatment of refractory status epilepticus. In addition, ECT might be applied to hyperkinetic movement and psychiatric symptoms of encephalitis. We also investigated the anticonvulsant mechanism of ECT and how it controls encephalitis symptoms.
电休克疗法（ECT）是治疗难治性精神疾病广泛应用的一种治疗选择。ECT通过电刺激诱发短暂的可控性癫痫发作来治疗精神症状，但ECT一般不会引起癫痫持续状态或癫痫。然而，多项研究报告了ECT后出现癫痫持续状态的病例。本综述旨在确定ECT后癫痫发生的机制及神经生物学变化。与ECT引发癫痫不同，有几例报告称ECT成功用于治疗难治性癫痫持续状态。此外，ECT可能适用于脑炎的运动亢进和精神症状。我们还研究了ECT的抗惊厥机制及其如何控制脑炎症状。
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