应用扫频源光学相干断层扫描测量血液透析对视盘周围脉络膜厚度的影响。
Effect of Hemodialysis on Peripapillary Choroidal Thickness Measured by Swept-Source Optical Coherence Tomography.
机构信息
Department of Ophthalmology.
Department of Ophthalmology, Hanyang University Seoul Hospital, Seoul.
出版信息
J Glaucoma. 2021 Jun 1;30(6):459-464. doi: 10.1097/IJG.0000000000001762.
PURPOSE
The aim was to investigate the effects of hemodialysis (HD) on peripapillary choroidal thickness (PCT) by swept-source optical coherence tomography and on other ophthalmologic parameters in patients with end-stage kidney disease.
MATERIALS AND METHODS
This was a prospective observational study. The authors evaluated 29 patients who underwent HD for end-stage kidney disease. Detailed ophthalmologic examinations and swept-source optical coherence tomography were performed immediately before and after HD. PCT was measured using the modification tool in the built-in OCT image viewer program. Changes in PCT before and after HD were statistically analyzed.
RESULTS
The average PCT significantly decreased from 127.3±49.2 μm before HD to 117.1±50.9 μm after HD (P<0.001). A significant correlation was found between changes in PCT and macular choroidal thickness (ρ=0.547, P=0.002). Changes in mean ocular perfusion pressure did not significantly correlate with changes in PCT (ρ=-0.049, P=0.803).
CONCLUSIONS
PCT significantly decreased after HD. HD could influence the optic nerve head and its surrounding structures.
目的
本研究旨在通过扫频源光相干断层扫描（OCT）观察血液透析（HD）对终末期肾病患者视盘周围脉络膜厚度（PCT）及其他眼科参数的影响。
材料和方法
这是一项前瞻性观察研究。作者评估了 29 例接受 HD 治疗的终末期肾病患者。在 HD 治疗前后均进行详细的眼科检查和扫频源 OCT 检查。使用内置 OCT 图像查看器程序中的修正工具测量 PCT。统计分析 HD 前后 PCT 的变化。
结果
HD 治疗前平均 PCT 为 127.3±49.2μm，治疗后为 117.1±50.9μm，明显降低（P<0.001）。PCT 的变化与黄斑脉络膜厚度的变化呈显著相关（ρ=0.547，P=0.002）。平均眼灌注压的变化与 PCT 的变化无显著相关性（ρ=-0.049，P=0.803）。
结论
HD 治疗后 PCT 明显降低。HD 可能影响视神经头及其周围结构。
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