Protsyk Olena, Lacorzana Javier
Department of Ophthalmology, Jaen University Hospital, Jaen, Spain.
Doctoral Program in Clinical Medicine and Public Health, University of Granada, Granada, Spain.
Indian J Ophthalmol. 2025 May 1;73(5):648-655. doi: 10.4103/IJO.IJO_1450_23. Epub 2025 Apr 24.
The purpose of this study was to examine the effects of hemodialysis on the eye and its long-term consequences. Hemodialysis is a process that purifies the blood and maintains the balance of water, solutes, acid-base, and electrolytes. The eye, being primarily composed of fluid, has been speculated to be affected by this technique. To analyze these effects, a literature review was conducted, focusing on the anatomical structures, functions, and changes in the eye following hemodialysis. The search for relevant articles was carried out on PubMed, including studies published in English between 2000 and 2023. The results of the review showed that certain observations such as visual acuity, refraction, intraocular pressure, biometric parameters, and retinal nerve fiber layer did not show significant timing-related impacts, or there were conflicting findings. However, a connection was established between hemodialysis sessions and visual fields, parameters of visual-evoked potential, intraocular pressure in glaucoma, tear break-up time, Schirmer's test values, choroidal thickness, flow velocities of vessels, and ocular perfusion pressure values. In conclusion, it was determined that hemodialysis sessions can cause fluctuations that may complicate the assessment of eye health. To obtain a more accurate baseline evaluation, it is recommended to schedule ophthalmological examinations, a few hours after the hemodialysis session. Additionally, it is important to provide appropriate management for dry eyes and ocular hypertension, particularly during hemodialysis sessions. Coordination of these examinations with the timing of renal replacement therapy is advised to ensure optimal patient care.
本研究的目的是探讨血液透析对眼睛的影响及其长期后果。血液透析是一个净化血液并维持水、溶质、酸碱和电解质平衡的过程。眼睛主要由液体组成,据推测会受到这种技术的影响。为了分析这些影响,我们进行了一项文献综述,重点关注血液透析后眼睛的解剖结构、功能和变化。我们在PubMed上搜索了相关文章,包括2000年至2023年期间发表的英文研究。综述结果表明,某些观察指标,如视力、屈光、眼压、生物测量参数和视网膜神经纤维层,未显示出与时间相关的显著影响,或者存在相互矛盾的研究结果。然而,血液透析疗程与视野、视觉诱发电位参数、青光眼眼压、泪膜破裂时间、泪液分泌试验值、脉络膜厚度、血管流速和眼灌注压值之间建立了联系。总之,研究确定血液透析疗程会引起波动,可能会使眼睛健康评估变得复杂。为了获得更准确的基线评估,建议在血液透析疗程结束后几个小时安排眼科检查。此外,对干眼症和高眼压症进行适当管理很重要,尤其是在血液透析疗程期间。建议将这些检查与肾脏替代治疗的时间进行协调,以确保为患者提供最佳护理。