• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在 COVID-19 疫情期间,对不合作的儿科患者进行牙齿治疗时,吸入氧化亚氮和氧气进行意识镇静的临床效果。

Clinical effectiveness of inhalation conscious sedation with nitrous oxide and oxygen for dental treatment in uncooperative paediatric patients during COVID-19 outbreak.

机构信息

Department of Neuroscience, Reproductive and Oral Sciences, School of Paediatric Dentistry, University of Naples "Federico II", Naples, Italy - Staff Member of UNESCO Chair on Health Education and Sustainable Development, University of Naples, "Federico II", Naples, Italy.

Department of Neuroscience, Reproductive and Oral Sciences, School of Paediatric Dentistry, University of Naples "Federico II", Naples, Italy.

出版信息

Eur J Paediatr Dent. 2020 Dec;21(4):277-282. doi: 10.23804/ejpd.2020.21.04.4.

DOI:10.23804/ejpd.2020.21.04.4
PMID:33337902
Abstract

AIM

The aim of this study was to evaluate the features of inhalation conscious sedation for urgent dental treatments in uncooperative paediatric patients during COVID-19 outbreak.

MATERIALS AND METHODS

Forty-two uncooperative patients, attending primary and secondary schools, were submitted to emergency dental treatments with inhalation conscious sedation using nitrous oxide and oxygen during COVID-19 pandemic. Collected data included: number of working sessions, success/failure, adverse events, side effects, number of teeth treated; type of dental procedure. Parents filled in an e-mailed questionnaire on post-discharge children status to evaluate: pain; crying; fever; vomiting; headache; drowsiness; excitability; irritability; ability to eat; need for drugs.

RESULTS

One working session was carried out in 29 patients, 2 working sessions were carried out in 6 patients and 3 working sessions were carried out in 7 patients. Success rate was 87.1%. In relation to success, there was no statistically significant difference between males and females, healthy and disabled patients, respectively; while there was a statistically significant difference between patients attending primary and secondary schools (p=0.023). No adverse events occurred. The most frequent side effect was nausea. In relation to side effects, there was no statistically significant difference between males and females, healthy and disabled patients, patients attending primary and secondary schools, respectively. In relation to e-mailed questionnaires on post-discharge children status, 29.6% of the patients had pain, 22.2% vomited, 14.8% had headache, 18.5% experienced drowsiness, 29.6% failed to eating normally, 35.2% needed to take drugs. None of the patients cried, had a fever, exhibited irritability and excitability.

CONCLUSION

Inhalation conscious sedation is a safe, practical and effective procedure with minimal side effects to perform emergency dental treatments in uncooperative paediatric patients during COVID-19 outbreak.

摘要

目的

本研究旨在评估在 COVID-19 大流行期间,对不合 作的儿科患者进行紧急牙科治疗时使用吸入性镇静的特 点。

材料和方法

42 名不合 作的患者,来自小学和中学, 在 COVID-19 大流行期间接受了使用氧化亚氮和氧气的吸入 性镇静进行的紧急牙科治疗。收集的数据包括:工作次数、 成功/失败、不良事件、副作用、治疗的牙齿数量;牙科手 术类型。家长填写了一份关于出院后儿童状况的电子问卷, 以评估:疼痛;哭泣;发热;呕吐;头痛;困倦;兴奋;易 激惹;进食能力;需要药物。

结果

29 名患者进行了一次工作,6 名患者进行了两次 工作,7 名患者进行了三次工作。成功率为 87.1%。在成功 方面,男性和女性、健康和残疾患者之间没有统计学显 著差异;而在小学和中学患者之间存在统计学显著差异 (p=0.023)。没有不良事件发生。最常见的副作用是恶心。 在副作用方面,男性和女性、健康和残疾患者、小学和中 学患者之间没有统计学显著差异。关于出院后儿童状况 的电子问卷,29.6%的患者有疼痛,22.2%的患者呕吐,14.8%的患者头痛,18.5%的患者困倦,29.6%的患者无法正常 进食,35.2%的患者需要服药。没有患者哭泣、发热、表 现出发脾气和兴奋。

结论

在 COVID-19 大流行期间,对不合 作的儿科患者进行紧急牙科治疗时,吸入性镇静是一种安 全、实用且有效的方法,副作用最小。

相似文献

1
Clinical effectiveness of inhalation conscious sedation with nitrous oxide and oxygen for dental treatment in uncooperative paediatric patients during COVID-19 outbreak.在 COVID-19 疫情期间,对不合作的儿科患者进行牙齿治疗时,吸入氧化亚氮和氧气进行意识镇静的临床效果。
Eur J Paediatr Dent. 2020 Dec;21(4):277-282. doi: 10.23804/ejpd.2020.21.04.4.
2
Inhalation Conscious Sedation with Nitrous Oxide and Oxygen as Alternative to General Anesthesia in Precooperative, Fearful, and Disabled Pediatric Dental Patients: A Large Survey on 688 Working Sessions.吸入性一氧化二氮和氧气镇静在术前恐惧和残疾的小儿牙科患者中替代全身麻醉:688 个工作时段的大型调查。
Biomed Res Int. 2016;2016:7289310. doi: 10.1155/2016/7289310. Epub 2016 Sep 26.
3
Comparison of oral midazolam with combination of oral midazolam and nitrous oxide inhalation in relation to safety of dental sedation in young children.口服咪达唑仑与口服咪达唑仑联合氧化亚氮吸入用于幼儿牙科镇静安全性的比较。
Odontostomatol Trop. 2011 Sep;34(135):33-41.
4
Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children.口服咪达唑仑与口服咪达唑仑联合一氧化二氮-氧气吸入用于幼儿牙科镇静效果的比较。
J Indian Soc Pedod Prev Dent. 2009 Jan-Mar;27(1):9-16. doi: 10.4103/0970-4388.50810.
5
A comparison of the sedative effect of oral versus nasal midazolam combined with nitrous oxide in uncooperative children.口服与鼻内咪达唑仑联合一氧化二氮对不合作儿童镇静效果的比较。
Eur Arch Paediatr Dent. 2015 Oct;16(5):417-24. doi: 10.1007/s40368-015-0187-7. Epub 2015 May 5.
6
The safety and efficacy of intranasal midazolam sedation combined with inhalation sedation with nitrous oxide and oxygen in paediatric dental patients as an alternative to general anaesthesia.鼻内咪达唑仑镇静联合一氧化二氮与氧气吸入镇静在儿科牙科患者中作为全身麻醉替代方法的安全性和有效性。
SAAD Dig. 2010 Jan;26:12-22.
7
Effectiveness and Safety of Intravenous Sedation with Propofol in Non-Operating Room Anesthesia (NORA) for Dental Treatment in Uncooperative Paediatric Patients.丙泊酚静脉镇静用于不合作儿科患者牙科治疗的非手术室麻醉(NORA)的有效性和安全性
Children (Basel). 2021 Jul 28;8(8):648. doi: 10.3390/children8080648.
8
Modification of behavior with 50% nitrous oxide/oxygen conscious sedation over repeated visits for dental treatment a 3-year prospective study.在多次牙科治疗就诊期间使用50%氧化亚氮/氧气清醒镇静对行为的改变:一项为期3年的前瞻性研究
J Clin Psychopharmacol. 2006 Oct;26(5):474-81. doi: 10.1097/01.jcp.0000236660.01039.eb.
9
A clinical trial of efficacy and safety of inhalation sedation with a 50% nitrous oxide/oxygen premix (Kalinox™) in general practice.一项关于 50%氧化亚氮/氧气预混气体(Kalinox™)吸入镇静在普通实践中的疗效和安全性的临床试验。
Clin Oral Investig. 2012 Apr;16(2):633-42. doi: 10.1007/s00784-011-0550-y. Epub 2011 Mar 29.
10
Conscious sedation of pediatric dental patients using chloral hydrate, hydroxyzine, and nitrous oxide--a retrospective study of 382 sedations.使用水合氯醛、羟嗪和一氧化二氮对儿童牙科患者进行清醒镇静——382例镇静的回顾性研究
Pediatr Dent. 1995 Nov-Dec;17(7):424-31.

引用本文的文献

1
Analgesia and sedative effects of a fixed nitrous oxide/oxygen mixture on supragingival scaling patients: a study protocol for a randomised controlled trial.固定比例一氧化二氮/氧气混合气体对龈上洁治患者的镇痛和镇静效果:一项随机对照试验的研究方案
BMJ Open. 2025 Jul 8;15(7):e096654. doi: 10.1136/bmjopen-2024-096654.
2
Equimolar oxygen-nitrous oxide (EMONO) in dental pediatric care: which patients achieve therapeutic effects? A French national exploratory prospective observational multicenter study.牙科儿科护理中使用等摩尔氧-氧化亚氮(EMONO):哪些患者能获得治疗效果?一项法国全国性探索性前瞻性观察性多中心研究。
Eur Arch Paediatr Dent. 2025 Feb;26(1):149-158. doi: 10.1007/s40368-024-00950-2. Epub 2024 Nov 15.
3
Analgesic effect of nitrous oxide during manual therapy after anterior cruciate ligament reconstruction: a study protocol for a randomized controlled trial.
前交叉韧带重建后手法治疗时氧化亚氮的镇痛效果:一项随机对照试验研究方案。
Trials. 2023 Nov 27;24(1):764. doi: 10.1186/s13063-023-07732-z.
4
Efficacy of nitrous oxide in adults undergoing puncture biopsy: A systematic review and meta-analysis of randomized controlled trials.笑气用于成人穿刺活检的疗效:随机对照试验的系统评价和荟萃分析。
PLoS One. 2023 Jun 6;18(6):e0286713. doi: 10.1371/journal.pone.0286713. eCollection 2023.
5
Behavioral Modifications in Children after Repeated Sedation with Nitrous Oxide for Dental Treatment: A Retrospective Study.反复吸入笑气镇静后儿童行为改变的回顾性研究。
Int J Environ Res Public Health. 2023 Feb 24;20(5):4037. doi: 10.3390/ijerph20054037.
6
Impact of Covid-19 pandemic on children with special needs requiring general anaesthesia for the treatment of dental disease: the experience of the Brescia Children's Hospital, Lombardy, Italy.新冠大流行对有特殊需要的儿童的影响,这些儿童因牙科疾病需要全身麻醉治疗:意大利伦巴第布雷西亚儿童医院的经验。
Eur Arch Paediatr Dent. 2023 Feb;24(1):133-138. doi: 10.1007/s40368-022-00770-2. Epub 2022 Nov 24.
7
Effectiveness and Safety of Intravenous Sedation with Propofol in Non-Operating Room Anesthesia (NORA) for Dental Treatment in Uncooperative Paediatric Patients.丙泊酚静脉镇静用于不合作儿科患者牙科治疗的非手术室麻醉(NORA)的有效性和安全性
Children (Basel). 2021 Jul 28;8(8):648. doi: 10.3390/children8080648.