Chemical Regulation and Food Safety, Exponent Inc , Washington, DC, USA.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Feb;38(2):181-194. doi: 10.1080/19440049.2020.1846083. Epub 2020 Dec 18.
Estimated intake of six low and no-calorie sweeteners (LNCS) (acesulfame potassium, aspartame, cyclamate, saccharin, steviol glycosides and sucralose) from processed foods and beverages, as well as from tabletop sweeteners uses, by the Brazilian population were derived and compared to the respective Acceptable Daily Intake (ADI). The estimates were based on dietary consumption data from a nationwide cross-sectional survey conducted by the Instituto Brasileiro de Geografia e Estatística (IBGE) in 2008-2009 and LNCS use rates and associated market share information based on data provided by Brazilian industry members. Two intake scenarios were considered: a conservative brand loyal consumer scenario that assumes all LNCS-containing foods and beverages and tabletop sweeteners contain the maximum reported LNCS concentrations (Scenario A) and a scenario representative of the general consumer population that uses a market share weighted average of the reported concentrations (Scenario B). Intake estimates were derived for the total Brazilian population (age 10 + y), and for the subpopulations of adolescents (10-18y), adults (19-59y), and older adults (60 + y). Intake of LNCS up to the 95 percentile did not exceed their respective ADI for all subpopulations considered, in either the general consumer scenario or the brand loyal scenario. Among consumers age 10 + y, the 95 percentile intakes of the various LNCS ranged from 6.8% to 54% of their respective ADI for the brand loyal scenario and from <1% to 6.0% of their respective ADIs for the general consumer scenario.
估算了巴西人口从加工食品和饮料以及餐桌甜味剂中摄入的六种低热量和无热量甜味剂(LNCS)(乙酰磺胺酸钾、阿斯巴甜、环己基氨基磺酸钠、糖精、甜菊糖甙和三氯蔗糖),并与各自的可接受日摄入量(ADI)进行了比较。这些估计数是基于巴西地理与统计研究所(IBGE)于 2008-2009 年进行的一项全国性横断面调查的饮食消费数据,以及基于巴西行业成员提供的使用率和相关市场份额信息的 LNCS 用量。考虑了两种摄入情况:一种是假设所有含 LNCS 的食品和饮料以及餐桌甜味剂都含有报告的 LNCS 最大浓度的保守品牌忠实消费者情景(情景 A),另一种是代表一般消费者人群使用报告浓度的市场份额加权平均值的情景(情景 B)。为巴西总人口(10 岁及以上)以及青少年(10-18 岁)、成年人(19-59 岁)和老年人(60 岁及以上)亚群计算了 LNCS 的摄入量估计值。在考虑的所有亚群中,无论是在一般消费者情景还是在品牌忠实消费者情景下,LNCS 的摄入量均未超过其各自 ADI 的 95 百分位。在 10 岁及以上的消费者中,各种 LNCS 的 95 百分位摄入量在品牌忠实消费者情景下,从各自 ADI 的 6.8%到 54%不等,在一般消费者情景下,从各自 ADI 的<1%到 6.0%不等。