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巴西亚马逊地区人类因接触染色毒蛙(Dendrobates tinctorius (SCHNEIDER, 1799))而中毒的报告(两栖纲:箭毒蛙科)。

Report of envenomation in humans by handling a dyeing poison frog Dendrobates tinctorius (SCHNEIDER, 1799) (Anura: Dendrobatidae) in the Amazon, Brazil.

机构信息

Universidade de Brasília, Laboratório de Anatomia Comparada, Brasília, DF, Brasil.

Universidade de Brasília, Laboratório de Planejamento para a Conservação da Biodiversidade, Brasília, DF, Brasil.

出版信息

Rev Soc Bras Med Trop. 2020 Dec 21;54:e04612020. doi: 10.1590/0037-8682-0461-2020. eCollection 2020.

DOI:10.1590/0037-8682-0461-2020
PMID:33338114
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7747814/
Abstract

We report a case of envenomation by Dendrobates tinctorius in the northwest of the Amazon Forest. The patients were two men, who presented with numbness in the right arm and slight numbness in the lower lip, respectively. Dendrobates tinctorius secretions contain pumiliotoxin, one of several toxins found in the dendrobatidis skin, which interferes with muscle contraction and causes locomotor difficulties. Although Dendrobatidae is a family of anurans known for their venom, few studies describe the symptoms of envenomation in humans.

摘要

我们报告了一起亚马逊森林西北部的哥伦比亚金色箭毒蛙(Dendrobates tinctorius)咬伤的病例。这两名患者分别出现右手麻木和下唇轻微麻木的症状。哥伦比亚金色箭毒蛙的分泌物中含有蓬毒素,这是几种存在于箭毒蛙皮肤中的毒素之一,它会干扰肌肉收缩并导致运动障碍。尽管蟾科是一种以毒液而闻名的蛙类,但很少有研究描述人类中毒的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853e/7747814/9c978b902264/1678-9849-rsbmt-54-e04612020-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853e/7747814/9c978b902264/1678-9849-rsbmt-54-e04612020-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853e/7747814/9c978b902264/1678-9849-rsbmt-54-e04612020-gf1.jpg

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本文引用的文献

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Forensic Sci Med Pathol. 2020 Jun;16(2):205-206. doi: 10.1007/s12024-019-00192-5. Epub 2019 Oct 19.
2
"Kambô" frog (Phyllomedusa bicolor): use in folk medicine and potential health risks.“坎波”蛙(双色叶泡蛙):在民间医学中的应用及潜在健康风险。
Rev Soc Bras Med Trop. 2019 Mar 28;52:e20180467. doi: 10.1590/0037-8682-0467-2018.
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Evolution of dietary specialization and chemical defense in poison frogs (Dendrobatidae): a comparative analysis.
箭毒蛙(树棘蛙科)饮食特化与化学防御的进化:一项比较分析
Am Nat. 2005 Jan;165(1):56-69. doi: 10.1086/426599. Epub 2004 Nov 12.
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Alkaloids of neotropical poison frogs (Dendrobatidae).
Fortschr Chem Org Naturst. 1982;41:205-340. doi: 10.1007/978-3-7091-8656-5_6.