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心肌梗死后心肌病与 SARS-CoV-2 感染的相关性。

Correlation between takotsubo cardiomyopathy and SARS-CoV-2 infection.

机构信息

Maria Sklodowska-Curie Medical Academy, Warsaw, Poland; Bialystok Oncology Center, Bialystok, Poland; Polish Society of Disaster Medicine, Warsaw, Poland.

First Chair and Department of Cardiology, Medical University of Warsaw, Poland.

出版信息

Med Hypotheses. 2021 Jan;146:110454. doi: 10.1016/j.mehy.2020.110454. Epub 2020 Dec 9.

Abstract

Takotsubo cardiomyopathy (TTS), known as stress cardiomyopathy, is a rare disorder characterized by acute and transient left ventricular systolic and diastolic dysfunction, often associated with a stressful, emotional or physical event. TTS may be closely related to SARS-CoV-2 infection and the ongoing pandemic. The enormous emotional stress caused by the pandemic and respiratory infections caused by SARS-CoV-2 could be potential triggers for TTS. The case series cited above implicates that TTS should be considered in the differential diagnosis across the entire spectrum of myocardial injury in SARS-CoV-2 infected patients. Myocardial damage associated with SARS-CoV-2 infection is usually attributed to sepsis, hypoxemia, coronary artery disease, and myocarditis. We hypothesize that TTS may also play a role among these lesions.

摘要

心尖球形综合征(TTS),又称应激性心肌病,是一种罕见的疾病,其特征为急性、短暂的左心室收缩和舒张功能障碍,常与应激性、情绪性或身体性事件相关。TTS 可能与 SARS-CoV-2 感染和持续的大流行密切相关。大流行造成的巨大情绪压力和 SARS-CoV-2 引起的呼吸道感染可能是 TTS 的潜在触发因素。上述病例系列表明,在 SARS-CoV-2 感染患者的整个心肌损伤谱中,应考虑将 TTS 作为鉴别诊断。与 SARS-CoV-2 感染相关的心肌损伤通常归因于败血症、低氧血症、冠状动脉疾病和心肌炎。我们假设 TTS 在这些病变中也可能起作用。

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