Department of Cardiology, Galilee Medical Center, Nahariya, Israel.
Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.
Isr Med Assoc J. 2021 Mar;23(3):149-152.
Takotsubo syndrome (TTS) is a non-ischemic cardiomyopathy characterized by an acute reversible left ventricular dysfunction with typical apical ballooning, usually with subsequent complete spontaneous recovery. TTS may be triggered by several physical and emotional stressors. The name Covidsubo was recently adopted to describe this emerging entity. TTS during quarantine may be a reasonable outcome of the overwhelming stress and fear of this pandemic. However, according to the current literature, conflicting results have been reported regarding the incidence of this syndrome during the first wave of the pandemic, and further studies are needed. High index of suspicion is needed to identify patients during the next waves of the pandemic, particularly given the need for minimizing imaging modalities and contact with the patients.
To describe two cases of TTS triggered by quarantine during the coronavirus disease-2019 (COVID-19) pandemic.
Two patients (age 81 years and 70 years) were admitted to our medical center with severe chest pain with normal blood pressure and heart rate.
TTS should always be in the differential diagnosis in patients presenting with chest pain suspected to be from coronary origin. Based on the typical clinical, echocardiographic, and angiographic findings, we assumed TTS.
The only prominent stressor in the two cases in this article was the stress accompanying quarantine.
Takotsubo 综合征（TTS）是一种非缺血性心肌病，其特征为急性可逆性左心室功能障碍伴典型的顶端球囊样变，通常随后完全自发恢复。TTS 可由多种躯体和精神应激源引发。最近采用 Covidsubo 这个名称来描述这一新兴病症。隔离期间发生的 TTS 可能是这种大流行带来的压倒性压力和恐惧的合理结果。然而，根据目前的文献，关于大流行第一波期间该综合征的发病率，报告结果相互矛盾，需要进一步研究。在下一波大流行期间，需要高度怀疑该病以识别患者，特别是需要尽量减少影像学检查和与患者接触。
描述两例在 2019 冠状病毒病（COVID-19）大流行期间因隔离而引发的 Takotsubo 综合征（TTS）病例。
两名患者（年龄分别为 81 岁和 70 岁）因严重胸痛、血压和心率正常而被收入我院。
在怀疑因冠状动脉起源而发生胸痛的患者中，TTS 始终应列入鉴别诊断。根据典型的临床、超声心动图和血管造影表现，我们假设为 TTS。
本文中两例患者唯一突出的应激源是隔离带来的压力。
