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在巴基斯坦开伯尔-普赫图赫瓦省本努地区,使用世卫组织疫苗犹豫工具,评估常规免疫中父母拒绝率及其相关因素的横断面研究。

Prevalence of Parental refusal rate and its associated factors in routine immunization by using WHO Vaccine Hesitancy tool: A Cross sectional study at district Bannu, KP, Pakistan.

机构信息

Khyber College of Dentistry, Peshawar, Khyber Pakhtunkhwa, Pakistan.

Khyber Medical University, Peshawar, Khyber Pakhtunkhwa, Pakistan.

出版信息

Int J Infect Dis. 2021 Mar;104:117-124. doi: 10.1016/j.ijid.2020.12.029. Epub 2020 Dec 17.

DOI:10.1016/j.ijid.2020.12.029
PMID:33340667
Abstract

OBJECTIVE

To determine the vaccination refusal rate, associated factors and perceptions of parents who refused routine immunization for their children using the World Health Organization (WHO) SAGE Working Group on Vaccine Hesitancy Survey Tool.

MATERIALS AND METHODS

A cross-sectional survey was conducted using multi-stage cluster sampling in Bannu District, Khyber Pakhtunkhwa Province, Pakistan from March 2019 to July 2019. A WHO validated questionaire was used. The outcome variable was parental refusal of routine immunization of their children. Logistic regression was performed for associations, and multi-regression was applied to identify any confounders.

RESULTS

Of 610 parents, 170 (27.9%) refused vaccination of their children. Of these, the majority of mothers had no education [n = 145 (85.3%); p = 0.03], and mothers were less likely to own a mobile phone than fathers [24 (14.1%) vs 152 (89.4%); p ≤ 0.001]. The vaccination refusal rate was higher in parents with food security [n = 88 (51.8%)] compared with parents with minimal food insecurity [n = 62 (36.5%)] and high food insecurity [20 (11.8%); p ≤ 0.05)]. On multi-variate logistic regression, fathers who were employed [adjusted odds ratio (OR) 0.59, 95% confidence interval (CI) 0.37-0.94; p = 0.02] and had a high level of education (adjusted OR 0.21, 95% CI 0.08-0.50; p ≤ 0.001) were less likely to refuse vaccination of their children. Parents with high food insecurity were more likely to refuse vaccination of their children (adjusted OR 2.2, 95% CI 1.0-0.50; p = 0.04) compared with parents with minimal food insecurity (adjusted OR 1.6, 95% CI 1.0-2.5; p = 0.02).

CONCLUSION

The vaccination refusal rate was very high among parents, and this was associated with inability to read or write, no education, owning a mobile phone, unemployment and food security.

摘要

目的

使用世界卫生组织(WHO)疫苗犹豫工作组疫苗犹豫调查工具,确定拒绝为子女常规免疫接种的父母的疫苗接种拒绝率、相关因素和认知。

材料和方法

本横断面调查于 2019 年 3 月至 7 月在巴基斯坦开伯尔-普赫图赫瓦省班努地区采用多阶段聚类抽样方法进行。使用经过 WHO 验证的问卷。主要结局变量为父母拒绝为子女常规免疫接种。采用逻辑回归分析相关性,并应用多元回归分析确定任何混杂因素。

结果

在 610 名父母中,有 170 名(27.9%)拒绝为子女接种疫苗。其中,大多数母亲没有受过教育[145 名(85.3%);p=0.03],拥有手机的母亲比父亲少[24 名(14.1%)比 152 名(89.4%);p≤0.001]。在食物有保障的父母中,疫苗接种拒绝率较高[88 名(51.8%)],而在食物基本有保障的父母中[62 名(36.5%)]和食物高度有保障的父母中[20 名(11.8%)]较低;p≤0.05]。多变量逻辑回归分析显示,有工作的父亲[调整后优势比(OR)0.59,95%置信区间(CI)0.37-0.94;p=0.02]和受过高等教育的父亲(调整后 OR 0.21,95%CI 0.08-0.50;p≤0.001)不太可能拒绝为子女接种疫苗。与食物基本有保障的父母相比,食物高度有保障的父母更有可能拒绝为子女接种疫苗[调整后 OR 2.2,95%CI 1.0-0.50;p=0.04](调整后 OR 1.6,95%CI 1.0-2.5;p=0.02)。

结论

父母的疫苗接种拒绝率非常高,这与读写能力、未受教育、拥有手机、失业和食物保障有关。

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