Department of Hand Surgery, Queen Margaret Hospital, Dunfermline, Whitefield Rd, Dunfermline KY12 0SU, United Kingdom.
Department of Orthopaedic Surgery, Glasgow Royal Infirmary, 84 Castle St, Glasgow G4 0SF, United Kingdom.
Hand Surg Rehabil. 2021 Jun;40(3):338-342. doi: 10.1016/j.hansur.2020.12.003. Epub 2020 Dec 16.
The aim of this study was to characterize the change in health-related quality of life following carpal tunnel decompression. Pre- and postoperative Euroqol 5 Dimensions scores were collected prospectively over three years. Outcomes were available for 435 of 563 patients (77%); mean age was 62 years. Comorbid status was described using the Charlson Comorbidity Index. Change in Euroqol 5 Dimensions scores declined with increasing age and Charlson Comorbidity Index: the greatest improvement in quality of life occurred in the youngest group (+0.07 vs. -0.07 in the oldest group; p < 0.001) and patients with the lowest Comorbidity Index (+0.05 vs. -0.07 in the highest comorbidity group; p < 0.001). Charlson Comorbidity Index was an independent predictor of worse change in Euroqol 5 Dimensions scores on regression analysis. Carpal tunnel decompression results in significant improvement in health-related quality of life in younger patients with minimal comorbidities, but not in older patients with more comorbidities. We advise interpreting the Euroqol 5 Dimensions scores with caution in this patient cohort. LEVEL OF EVIDENCE: III (cohort study).
本研究旨在描述腕管松解术后健康相关生活质量的变化。前瞻性地在三年内收集术前和术后欧洲五维健康量表评分。435 名 563 名患者（77%）的结果可用；平均年龄为 62 岁。使用 Charlson 合并症指数描述合并症状态。欧洲五维健康量表评分的变化随着年龄和 Charlson 合并症指数的增加而下降：生活质量的最大改善发生在最年轻的组（+0.07 与最年长组的-0.07 相比；p<0.001）和合并症指数最低的患者（+0.05 与最高合并症组的-0.07 相比；p<0.001）。Charlson 合并症指数是回归分析中欧洲五维健康量表评分变化更差的独立预测因子。腕管松解术可显著改善年轻、合并症少的患者的健康相关生活质量，但不能改善年龄较大、合并症较多的患者的生活质量。我们建议在该患者人群中谨慎解释欧洲五维健康量表评分。证据水平：III（队列研究）。
