Department of Neurology and Psychiatry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Hubei Provincial Hospital of Integrated Chinese and Western Medicine, 430015, China.
J Affect Disord. 2021 Feb 15;281:312-320. doi: 10.1016/j.jad.2020.11.118. Epub 2020 Dec 1.
This study aimed to explore the prevalence of psychological disorders and associated factors at different stages of the COVID-19 epidemic in China.
The mental health status of respondents was assessed via the Patient Health Questionnaire-9 (PHQ-9), Insomnia Severity Index (ISI) and the Generalized Anxiety Disorder 7 (GAD-7) scale.
5657 individuals participated in this study. History of chronic disease was a common risk factor for severe present depression (OR 2.2, 95% confidence interval [CI], 1.82-2.66, p < 0.001), anxiety (OR 2.41, 95% CI, 1.97-2.95, p < 0.001), and insomnia (OR 2.33, 95% CI, 1.83-2.95, p < 0.001) in the survey population. Female respondents had a higher risk of depression (OR 1.61, 95% CI, 1.39-1.87, p < 0.001) and anxiety (OR 1.35, 95% CI, 1.15-1.57, p < 0.001) than males. Among the medical workers, confirmed or suspected positive COVID-19 infection as associated with higher scores for depression (confirmed, OR 1.87; suspected, OR 4.13), anxiety (confirmed, OR 3.05; suspected, OR 3.07), and insomnia (confirmed, OR 3.46; suspected, OR 4.71).
The cross-sectional design of present study presents inference about causality. The present psychological assessment was based on an online survey and on self-report tools, albeit using established instruments. We cannot estimate the participation rate, since we cannot know how many potential subjects received and opened the link for the survey.
Females, non-medical workers and those with a history of chronic diseases have had higher risks for depression, insomnia, and anxiety. Positive COVID-19 infection status was associated with higher risk of depression, insomnia, and anxiety in medical workers.
本研究旨在探讨中国 COVID-19 疫情不同阶段心理障碍的患病率及相关因素。
采用患者健康问卷-9(PHQ-9)、失眠严重程度指数(ISI)和广泛性焦虑症 7 项量表(GAD-7)评估受访者的心理健康状况。
共有 5657 人参与了本研究。慢性病史是重度抑郁(OR 2.2,95%置信区间 [CI],1.82-2.66,p<0.001)、焦虑(OR 2.41,95% CI,1.97-2.95,p<0.001)和失眠(OR 2.33,95% CI,1.83-2.95,p<0.001)在调查人群中共同的高危因素。女性受访者患抑郁(OR 1.61,95% CI,1.39-1.87,p<0.001)和焦虑(OR 1.35,95% CI,1.15-1.57,p<0.001)的风险高于男性。在医务人员中,确诊或疑似 COVID-19 感染与抑郁(确诊,OR 1.87;疑似,OR 4.13)、焦虑(确诊,OR 3.05;疑似,OR 3.07)和失眠(确诊,OR 3.46;疑似,OR 4.71)评分较高相关。
本研究的横断面设计提出了因果关系的推断。目前的心理评估是基于在线调查和自我报告工具,尽管使用了既定的工具。我们无法估计参与率,因为我们不知道有多少潜在的对象收到并打开了调查链接。
女性、非医务人员和患有慢性病的人患抑郁、失眠和焦虑的风险更高。COVID-19 阳性感染状态与医务人员抑郁、失眠和焦虑风险增加相关。