Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, PO box 151, Beer-Sheva, Israel.
Department of psychiatry, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Arch Womens Ment Health. 2020 Dec;23(6):767-773. doi: 10.1007/s00737-020-01075-3. Epub 2020 Oct 12.
The aim of the current study was to assess the risk for post-partum depression among women delivering during the COVID-19 pandemic as compared to the risk among women delivering before the COVID-19 pandemic. A cohort study was performed among women delivering singletons at term which were recruited in the maternity wards of the Soroka University Medical Center. Recruitment was done during the COVID-19 strict isolation period (March 18 and April 29, 2020). Women delivering during the COVID-19 pandemic completed the Edinburgh Postnatal Depression Scale (EPDS), and the results were compared to women delivering at the same medical center before the COVID-19 pandemic. Multivariable logistic regression models were constructed to control for potential confounders. A total of 223 women who delivered during the COVID-19 strict isolation period were recruited. Women delivering during the COVID-19 pandemic had lower risk of having a high (> 10) or very high (≥ 13) EPDS score as compared with women delivering before the COVID-19 pandemic (16.7% vs 31.3%, p = 0.002, and 6.8% vs 15.2%, p = 0.014, for EPDS ≥ 10 and EPDS ≥ 13, respectively). These results remained similar in the multivariable logistic regression models, for both EPDS score ≥ 10 and EPDS score ≥ 13, while controlling for maternal age, ethnicity, marital status, and adverse pregnancy outcomes (adjusted OR 0.4, 95% CI 0.23-0.70, p = 0.001 and adjusted OR 0.3, 95% CI 0.15-0.74, p = 0.007 for EPDS score > 10 and > 13, respectively). In our population, delivering during the COVID-19 pandemic was independently associated with lower risk of post-partum depression.
本研究旨在评估与 COVID-19 大流行前相比，COVID-19 大流行期间分娩的女性产后抑郁的风险。这是一项在索罗卡大学医学中心的产科病房招募单胎足月分娩女性的队列研究。招募工作是在 COVID-19 严格隔离期间（2020 年 3 月 18 日至 4 月 29 日）进行的。在 COVID-19 大流行期间分娩的女性完成了爱丁堡产后抑郁量表（EPDS），并将结果与 COVID-19 大流行前在同一医疗中心分娩的女性进行比较。构建了多变量逻辑回归模型来控制潜在的混杂因素。共招募了 223 名在 COVID-19 严格隔离期间分娩的女性。与 COVID-19 大流行前分娩的女性相比，COVID-19 大流行期间分娩的女性发生 EPDS 评分较高（>10）或非常高（≥13）的风险较低（16.7%比 31.3%，p=0.002，和 6.8%比 15.2%，p=0.014，分别用于 EPDS≥10 和 EPDS≥13）。在多变量逻辑回归模型中，这两种结果均相似，分别用于 EPDS 评分≥10 和 EPDS 评分≥13，同时控制了母亲年龄、种族、婚姻状况和不良妊娠结局（调整后的 OR 0.4，95%CI 0.23-0.70，p=0.001 和调整后的 OR 0.3，95%CI 0.15-0.74，p=0.007，分别用于 EPDS 评分>10 和>13）。在我们的人群中，COVID-19 大流行期间分娩与产后抑郁风险降低独立相关。
