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抗磷脂综合征中的动脉血栓形成:临床方法和治疗。系统评价。

Arterial thrombosis in antiphospholipid syndrome (APS): Clinical approach and treatment. A systematic review.

机构信息

Thrombosis Research Laboratory, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padova, Padua, Italy.

Department of Cardiovascular Surgery, The First Affiliated Hospital of Xiamen University, Xiamen, China.

出版信息

Blood Rev. 2021 Jul;48:100788. doi: 10.1016/j.blre.2020.100788. Epub 2020 Dec 13.

Abstract

Thrombotic Antiphospholipid Syndrome (APS) is a condition affecting young individuals in whom a thromboembolic event occurs in the presence of circulating antiphospholipid antibodies (aPL). An extensive body of literature has covered the most common clinical presentation of the syndrome, venous thromboembolism. Arterial thrombosis in APS, a lesser clinical expression, is less studied. This review will concentrate on the body of literature concerning pathogenesis, clinical presentation and management of arterial thrombosis in APS.

摘要

血栓性抗磷脂综合征(APS)是一种影响年轻人的疾病,其特征是在循环抗磷脂抗体(aPL)存在的情况下发生血栓栓塞事件。大量文献已经涵盖了该综合征最常见的临床表现,即静脉血栓栓塞。APS 中的动脉血栓形成是一种较少见的临床表现,研究较少。这篇综述将集中讨论关于 APS 中动脉血栓形成的发病机制、临床表现和治疗的文献。

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