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未切除间置空肠袋与食管胃吻合术和空肠对食管及残胃的双重吻合术:近端胃切除术后消化道重建的一种创新方法。

Uncut interposed jejunum pouch versus esophago-gastrostomy and double anastomoses of jejunum to the esophagus and residual stomach: An innovative method of digestive tract reconstruction following proximal gastrectomy.

机构信息

Department of General Surgery, Dujiangyan Shoujia Hospital, Chengdu, Sichuan Province, China.

Department of Medical Laboratory, The General Hospital of Western Theater Command, Chengdu, Sichuan Province, China.

出版信息

Asian J Surg. 2023 Oct;46(10):4196-4201. doi: 10.1016/j.asjsur.2022.11.067. Epub 2022 Nov 28.

Abstract

AIM

An innovative method of digestive tract reconstruction following proximal gastrectomy, the uncut interposed jejunum pouch, esophagus and residual stomach double anastomosis(Uncut-D), was established in recent years. In order to fully clarify the superiority of the procedure, this study has conducted a systematic analysis and thorough discussion.

METHODS

118 patients with adenocarcinoma of the esophagogastric junction who underwent proximal gastrectomy were enrolled in this study. According to the methods of digestive tract reconstruction, these patients were divided into three groups: Uncut-D(n = 43), esophagogastrostomy (EG, n = 36), jejunal interposition (JI, n = 39).The preoperative indicators, surgical complications and related indicators of postoperative quality of life were analyzed.

RESULTS

There were no significant differences in preoperative data among all groups (P > 0.05); The digestive tract reconstruction time in Uncut-D group was more than that in EG group, and less than that in JI group (P < 0.05). The incidence of esophageal anastomotic stenosis in Uncut-D group was significantly lower than that in EG group (P < 0.05); In Uncut-D group, the incidence of reflux esophagitis, postoperative nutrition index(PNI), weight recovery and Visick classification were significantly better than those in EG group (P < 0.05), furthermore, the incidence of delayed gastric emptying,PNI and weight recovery were better than those in JI group (P < 0.05).

CONCLUSIONS

The Uncut-D procedure gave full play to jejunal continuity and the advantages of pouch, and played a valuable role in gastric and cardiac replacement, which significantly reduced long-term complications, improved postoperative nutritional status of patients and long-term quality of life.

摘要

目的

近年来,一种创新性的近端胃切除术后消化道重建方法——未切割间置空肠囊、食管和残胃双吻合术(Uncut-D)已经建立。为了充分阐明该术式的优越性,本研究进行了系统分析和深入讨论。

方法

本研究纳入了 118 例接受近端胃切除术的食管胃结合部腺癌患者。根据消化道重建方法,将这些患者分为三组:Uncut-D(n=43)、食管胃吻合术(EG,n=36)、空肠间置术(JI,n=39)。分析了术前指标、手术并发症和术后生活质量相关指标。

结果

三组患者术前资料比较差异均无统计学意义(P>0.05);Uncut-D 组消化道重建时间长于 EG 组,短于 JI 组(P<0.05)。Uncut-D 组食管吻合口狭窄发生率明显低于 EG 组(P<0.05);Uncut-D 组反流性食管炎、术后营养指数(PNI)、体质量恢复和 Visick 分级的发生率明显优于 EG 组(P<0.05),延迟胃排空、PNI 和体质量恢复的发生率优于 JI 组(P<0.05)。

结论

Uncut-D 术式充分发挥了空肠连续性和囊袋的优势,在胃和心脏替代方面发挥了重要作用,显著降低了长期并发症,改善了患者术后营养状况和长期生活质量。

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