Department of Surgical Oncology, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
J Cancer Res Ther. 2020 Oct-Dec;16(6):1528-1531. doi: 10.4103/jcrt.JCRT_176_19.
We present here a case of a 35-year-old woman diagnosed with primary neuroendocrine carcinoma of the breast (NECB) - small cell type. We discuss the importance of histological and molecular criteria for primary neuroendocrine mammary neoplasm, established by the World Health Organization in 2003 and 2012. We present information about differential diagnosis, prognostic factors, surgical treatment, adjuvant treatment, and novel therapies for primary NECB. Although this disease is not so uncommon but it is highly underreported and with consistent diagnostic criteria, surgeons should be able to keep this entity as differential diagnosis to enable them a timely treatment.
我们在此介绍了一例 35 岁女性，被诊断为原发性乳腺神经内分泌癌（NECB）-小细胞型。我们讨论了 2003 年和 2012 年世界卫生组织（WHO）确立的原发性神经内分泌乳腺肿瘤的组织学和分子标准的重要性。我们介绍了原发性 NECB 的鉴别诊断、预后因素、手术治疗、辅助治疗和新疗法的信息。虽然这种疾病并不常见，但由于诊断标准一致，报告率很低，因此外科医生应该能够将其作为鉴别诊断，以便及时进行治疗。
