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创伤后应激障碍中的苏达山克里亚瑜伽疗法:一项可行性研究。

Sudarshan Kriya Yoga Program in Posttraumatic Stress Disorder: A Feasibility Study.

作者信息

Vasudev Kamini, Ionson Emily, Inam Samin, Speechley Mark, Chaudhari Sumit, Ghodasara Sheena, Newman Ronnie I, Vasudev Akshya

机构信息

Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Department of Psychiatry, London Health Sciences Centre, London, ON, Canada.

出版信息

Int J Yoga. 2020 Sep-Dec;13(3):239-246. doi: 10.4103/ijoy.IJOY_16_20. Epub 2020 Sep 13.

Abstract

BACKGROUND

Sudarshan Kriya Yoga (SKY), a breath-based yoga intervention, has demonstrated safety and efficacy in posttraumatic stress disorder (PTSD) patients subsequent to natural disaster or war, but has not been explored in civilians with PTSD from a wider range of trauma. We hypothesized that it would be feasible to conduct a clinical trial of SKY in PTSD resulting from a wide range of trauma.

METHODS

Outcomes were feasibility measures including rates of enrollment and retention, adherence to study protocol; as well as changes in PTSD symptoms, other mood symptoms, and physiological measures. Male and female participants aged 18-75 years were enrolled in a feasibility trial. They attended a 6-day learning phase of SKY followed by 7 sessions over 11 weeks as an adjunct to their usual treatment.

RESULTS

Forty-seven participants were screened and 32 were enrolled over 9 months. Consistent with retention rates of other PTSD trials, 13 withdrew from the study prior to week 12. Twenty-one participants met intervention attendance requirements, completed 95% of planned study assessments and were included in final analyses. Participants experienced clinically significant decrease in PTSD symptoms on the posttraumatic stress disorder checklist (PCL-5) scores at week 12 mean difference, M (standard deviation [SD]) = -10.68 (14.03), = 0.004; Cohen's d = 0.58, which was sustained at week 24 M (SD) = -16.11 (15.20), < 0.001; Cohen's d = 0.91.

CONCLUSIONS

It is possible to conduct a clinical trial of SKY in a routine psychiatry clinic serving patients with PTSD due to a wide range of trauma. Future studies should include an RCT design.

摘要

背景

苏达山克里亚瑜伽(SKY)是一种基于呼吸的瑜伽干预方法,已在自然灾害或战争后的创伤后应激障碍(PTSD)患者中证明了安全性和有效性,但尚未在遭受更广泛创伤的PTSD平民患者中进行研究。我们假设对因广泛创伤导致的PTSD患者进行SKY临床试验是可行的。

方法

结果指标为可行性指标,包括入组率和留存率、对研究方案的依从性;以及PTSD症状、其他情绪症状和生理指标的变化。年龄在18 - 75岁的男性和女性参与者参加了一项可行性试验。他们参加了为期6天的SKY学习阶段,随后在11周内进行7次课程,作为其常规治疗的辅助。

结果

在9个月内,对47名参与者进行了筛查,32名参与者入组。与其他PTSD试验的留存率一致,13名参与者在第12周前退出研究。21名参与者达到干预出勤要求,完成了95%的计划研究评估,并被纳入最终分析。参与者在第12周时创伤后应激障碍检查表(PCL - 5)评分上的PTSD症状出现了临床上显著的下降,平均差异M(标准差[SD])=-10.68(14.03),P = 0.004;科恩d值= 0.58,在第24周时该差异持续存在,M(SD)=-16.11(15.20),P < 0.001;科恩d值= 0.91。

结论

在为因广泛创伤导致PTSD的患者服务的常规精神病诊所中进行SKY临床试验是可行的。未来的研究应采用随机对照试验(RCT)设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2c0/7735495/4f864bc58c59/IJY-13-239-g001.jpg

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