Doll D C, Grogan T M, Greenberg B R
Veterans Administration Medical Center, Phoenix, Arizona 85012.
Hematol Pathol. 1987;1(3):183-9.
A patient with a 3.5 year history of chronic myelomonocytic leukemia who transformed to malignant histiocytosis is reported. The terminal event was characterized by fever, hepatosplenomegaly, thrombocytopenia, and a leukemic blood picture. The pathogenesis of this terminal transformation and proposed future studies are discussed.