Kline-Fath Beth M, Bierbrauer Karin S, Calvo-Garcia Maria A, Nagaraj Usha D
Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
College of Medicine Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
Radiol Case Rep. 2020 Dec 11;16(2):392-395. doi: 10.1016/j.radcr.2020.12.006. eCollection 2021 Feb.
Meroanencephaly occurs when there is an incomplete open median calvarial defect. This condition, which is in the spectrum of anencephaly, results in ectopic brain without skin covering and a normal foramen magnum. We present a rare case of a female fetus with meroanencephaly referred to our institution at 24 weeks and imaged with both prenatal ultrasound and MRI, demonstrating an open neural tube defect in the high parietal area and lack of visualization of the supratentorial ventricular system. Postnatal the child survived and went on to require antibiotic therapy and closure of the defect without cerebral spinal fluid diversion but demonstrates severe permanent neurologic deficits.
半叶无脑畸形发生于存在不完全开放性颅骨正中缺损时。这种情况属于无脑畸形谱系，会导致脑异位且无皮肤覆盖，枕骨大孔正常。我们报告了一例罕见的半叶无脑畸形女性胎儿病例，该胎儿在孕24周时转诊至我院，接受了产前超声和MRI检查，显示顶叶上部区域存在开放性神经管缺陷，幕上脑室系统未见显示。出生后，患儿存活，随后需要抗生素治疗以及在未进行脑脊液分流的情况下闭合缺损，但仍表现出严重的永久性神经功能缺损。
