Gupta Devika, Chatterjee Tathagata, Tewari Rohit, Trehan Arti, Ahuja Anuradha
Army Hospital, Department of Laboratory Science & Molecular Medicine, New Delhi, India.
Army Hospital, Department of Respiratory Medicine, New Delhi, India.
Autops Case Rep. 2020 Sep 2;10(3):e2020199. doi: 10.4322/acr.2020.199.
We present the autopsy findings and differential diagnosis in a 42year old male who presented with fever and rapidly progressive respiratory symptoms like breathlessness, nonproductive cough and right sided chest pain. Initial imaging workup done at our hospital revealed a large unilateral tumor with tracheal shift. While being evaluated patient developed facial puffiness, tachypnea suggestive of superior vena cava obstruction. Antemortem biopsy of lung mass was attempted twice and that suggested malignant lesion. Unfortunately, the individual had a rapid downhill course following admission. Post mortem examination was conducted that on opening the thoracic cavity revealed total replacement of right lung tissue by a necrotic growth which was deeply adherent to the rib cage. The contralateral lung as well as all other visceral organs were unremarkable grossly. Histopathology confirmed primary Ewing sarcoma of the lung. We hereby, report a rare case of primary lung Ewing sarcoma diagnosed at autopsy.
我们展示了一名42岁男性的尸检结果及鉴别诊断情况，该男性出现发热以及如呼吸急促、干咳和右侧胸痛等快速进展的呼吸道症状。我院最初的影像学检查显示有一个巨大的单侧肿瘤并伴有气管移位。在评估过程中，患者出现面部肿胀、呼吸急促，提示上腔静脉阻塞。对肺部肿块进行了两次生前活检，结果提示为恶性病变。不幸的是，该患者入院后病情迅速恶化。进行了尸检，打开胸腔后发现右肺组织完全被坏死性肿物替代，该肿物与肋骨紧密粘连。对侧肺以及所有其他内脏器官大体上均无异常。组织病理学证实为原发性肺尤因肉瘤。我们在此报告一例在尸检时诊断出的罕见的原发性肺尤因肉瘤病例。
