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深色皮肤中的寻常狼疮:皮肤镜与组织病理学的不一致性。

Lupus Vulgaris in Darker Skin: Dermoscopic and Histopathologic Incongruity.

作者信息

Ankad Balachandra S, Adya Keshavmurthy A, Gaikwad Sakshi S, Inamadar Arun C, Manjula R

机构信息

Department of Dermatology, S. Nijalingappa Medical College, Bagalkot, Karnataka, India.

Department of Dermatology, Shri B M Patil Medical College Hospital and Research Centre, BLDE (Deemed to be University), Vijayapur, Karnataka, India.

出版信息

Indian Dermatol Online J. 2020 Nov 8;11(6):948-952. doi: 10.4103/idoj.IDOJ_100_20. eCollection 2020 Nov-Dec.

Abstract

INTRODUCTION

Lupus Vulgaris (LV) is the chronic, progressive, tissue destructive form of cutaneous tuberculosis. LV should be diagnosed and treated to prevent scaring and deformities. Histopathology is the gold standard for the diagnosis. Dermoscopy is helpful tool in diagnosing different dermatological condition. Here, dermoscopic and histopathogical correlation in LV was attempted.

MATERIALS AND METHODS

It was a cross sectional, observational study done from February 2019 to October 2019. Nineteen patients of LV were included. Dermlite 4 with attached smart phone (iphone) was employed. LV lesions were subjected to skin biopsy to confirm the diagnosis.

RESULTS

Study enrolled 19 patients, with 8males, 5 female and 6 children. Dermoscopy showed yellowish-white globules, white structureless areas and white scales were noted in 19 (100%) patients. Telangiectasias were seen in 16 (84.21%) patients as long linear, branching and short linear vessels. Pinkish-red background was noted in all patients (100% n=19). Newer observations included white shiny streaks, white rosettes and bluish hue. Age, sex, duration of lesions had no influence in the dermoscopic patterns. Discrepancy in dermoscopic-histopathologic correlation was noted. Facial lesions showed increased frequency of follicular plugs, patulous follicles and white rosettes.

CONCLUSION

Dermoscopy is widely gaining importance in the realm of dermatology. In this study, dermoscopy demonstrated characteristic patterns in LV. Thus, dermoscopy a non-invasive procedure can be used as diagnostic tool in many infective dermatoses.

摘要

引言

寻常狼疮(LV)是皮肤结核的慢性、进行性、组织破坏性形式。应诊断并治疗寻常狼疮以防止瘢痕形成和畸形。组织病理学是诊断的金标准。皮肤镜检查是诊断不同皮肤病的有用工具。在此,尝试对寻常狼疮进行皮肤镜检查与组织病理学的相关性研究。

材料与方法

这是一项于2019年2月至2019年10月进行的横断面观察性研究。纳入了19例寻常狼疮患者。使用配备智能手机(苹果手机)的Dermlite 4。对寻常狼疮病变进行皮肤活检以确诊。

结果

该研究纳入了19例患者,其中8例男性,5例女性和6例儿童。皮肤镜检查显示,19例(100%)患者出现黄白色小球、白色无结构区域和白色鳞屑。16例(84.21%)患者可见毛细血管扩张,表现为长直线状、分支状和短直线状血管。所有患者(100%,n = 19)均可见粉红红色背景。新的观察结果包括白色闪亮条纹、白色玫瑰花结和蓝色调。年龄、性别、病变持续时间对皮肤镜检查模式无影响。皮肤镜检查与组织病理学的相关性存在差异。面部病变中毛囊角栓、扩张毛囊和白色玫瑰花结的出现频率增加。

结论

皮肤镜检查在皮肤科领域的重要性日益凸显。在本研究中,皮肤镜检查显示了寻常狼疮的特征性模式。因此,皮肤镜检查作为一种非侵入性检查方法,可用于许多感染性皮肤病的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/7734991/4a17050e90da/IDOJ-11-948-g001.jpg

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