Bakulina N V, Simanenkov V I, Vorobyev S L, Tikhonov S V, Lishchuk N B, Bakulin I G
Mechnikov North-Western State Medical University.
National Center for Clinical Morphological Diagnostics.
Ter Arkh. 2020 Sep 3;92(8):100-107. doi: 10.26442/00403660.2020.08.000792.
The study of eosinophilic esophagitis has become a dynamic field with an evolving understanding of the pathogenesis, diagnosis, and treatment. Immunoglobulin G4 (IgG4)-related disease exhibits systemic involvement but very rarely involves the esophagus. The article presents a clinical case: the history of ulcer and stricture of the esophagus in a young man of 17 years. The patient was finally diagnosed with IgG4-related and eosinophilic esophagitis and showed a good response to corticosteroid therapy. We herein report a rare case of dysphagia associated with IgG4-related disease and eosinophilic. We presented a review of modern data on the relationship of eosinophilic esophagitis and pathological IgG4-response.
嗜酸性食管炎的研究已成为一个充满活力的领域，人们对其发病机制、诊断和治疗的认识不断发展。免疫球蛋白G4（IgG4）相关疾病表现为全身性受累，但很少累及食管。本文介绍了一例临床病例：一名17岁青年男性的食管溃疡和狭窄病史。该患者最终被诊断为IgG4相关性和嗜酸性食管炎，对皮质类固醇治疗反应良好。我们在此报告一例罕见的与IgG4相关疾病和嗜酸性粒细胞相关的吞咽困难病例。我们对嗜酸性食管炎与病理性IgG4反应之间关系的现代数据进行了综述。
