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[免疫功能低下患者和免疫功能正常个体感染性食管炎的评估与管理]

[Evaluation and management of infectious esophagitis in immunocompromised patients and immunocompetent individuals].

作者信息

Trukhmanov A S, Makushina A A, Storonova O A, Ivashkina N Y

机构信息

Sechenov First Moscow State Medical University (Sechenov University).

出版信息

Ter Arkh. 2020 Sep 3;92(8):108-117. doi: 10.26442/00403660.2020.08.000763.

Abstract

Among the many causes of the inflammatory process in the esophagus, infectious diseases are becoming increasingly important due to their steady growth. Previously esophageal infections have traditionally been associated with immunodeficiency syndromes, but now in clinical practice, these disorders are becoming increasingly recognized in immunocompetent individuals. Early diagnosis of infectious esophagitis is necessary to develop effective treatment tactics, and, as a result, reduce the risk of complications and adverse outcomes of the disease. This study reviewed the most clinical relevant pathogens of infectious esophagitis, both among patients with immunodeficiency and among healthy individuals. Specific diagnostic, risk factors, clinical presentation and therapeutic features were considered depending on the immune status of patients.

摘要

在食管炎症过程的众多病因中,传染病因其不断增加而变得愈发重要。以前,食管感染传统上与免疫缺陷综合征相关,但如今在临床实践中,免疫功能正常的个体中也越来越多地认识到这些疾病。感染性食管炎的早期诊断对于制定有效的治疗策略至关重要,从而降低疾病并发症和不良后果的风险。本研究回顾了免疫缺陷患者和健康个体中感染性食管炎最具临床相关性的病原体。根据患者的免疫状态考虑了具体的诊断、危险因素、临床表现和治疗特点。

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