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[增殖性玻璃体视网膜病变(PVR)手术:瘢痕之战:成功治疗PVR脱离的五个步骤]

[Proliferative vitreoretinopathy (PVR) surgery: Scar Wars : Five steps to successful treatment of PVR detachment].

作者信息

Priglinger S G, Siedlecki J, Hattenbach L-O, Grisanti S

机构信息

Augenklinik und Poliklinik des Klinikums der Universität München, LMU, Mathildenstr. 8, 80336, München, Deutschland.

Augenklinik Ludwigshafen, Ludwigshafen, Deutschland.

出版信息

Ophthalmologe. 2021 Jan;118(1):18-23. doi: 10.1007/s00347-020-01293-1.

DOI:10.1007/s00347-020-01293-1
PMID:33346893
Abstract

BACKGROUND

After initially successful surgery of retinal detachment, proliferative vitreoretinopathy (PVR) is the most common cause of renewed retinal detachment. With an incidence of 5-20% it represents a frequent surgical challenge based on a pronounced epiretinal, subretinal and intraretinal scar formation.

MATERIAL AND METHODS

The five most important steps leading to a successful repair of a PVR retinal detachment are described.

RESULTS

1. The basic prerequisite is the complete removal of the vitreous body in order to remove the substrate for proliferation of pathological cells. 2. Furthermore, the complete removal of all tractional PVR membranes is necessary. Subretinal PVR membranes that show no traction can be left in place. 3. The professional care of the macular is still important. As approximately 12% of all patients who undergo surgery for retinal detachment develop an epiretinal gliosis/macular pucker, peeling of the internal limiting membrane (ILM) is obligatory in cases of PVR. 4. Particularly in PVR detachment the mentioned surgical procedure is facilitated by the selection of suitable modern instruments, including wide-angle optics, such as the binocular indirect ophthalmomicroscope (BIOM), chandelier lights, perfluorocarbons (PFCL) and silicone oil. 5. Last but not least, the credo as much as necessary, as little as possible is of essential importance, as PVR eyes have usually been previously operated on and any further surgical intervention leads to subsequent inflammation and a persisting stimulation of the PVR reaction and further damage.

CONCLUSION

Following a few decisive rules and tips is a prerequisite for a successful reattachment in cases of PVR retinal detachment.

摘要

背景

视网膜脱离初次手术成功后,增殖性玻璃体视网膜病变(PVR)是视网膜再次脱离最常见的原因。其发病率为5%-20%,由于明显的视网膜前、视网膜下和视网膜内瘢痕形成,这是一个常见的手术挑战。

材料与方法

描述了成功修复PVR性视网膜脱离的五个最重要步骤。

结果

  1. 基本前提是彻底清除玻璃体,以去除病理性细胞增殖的底物。2. 此外,必须彻底清除所有牵引性PVR膜。无牵引的视网膜下PVR膜可予保留。3. 黄斑的专业护理仍然很重要。由于所有接受视网膜脱离手术的患者中约有12%会发生视网膜前胶质增生/黄斑皱襞,因此在PVR病例中必须剥除内界膜(ILM)。4. 特别是在PVR性脱离中,选用合适的现代器械有助于上述手术操作,包括广角光学设备,如双目间接检眼镜(BIOM)、吊灯式照明、全氟碳化合物(PFCL)和硅油。5. 最后但同样重要的是,“尽可能多,尽可能少”的原则至关重要,因为PVR患者通常之前已接受过手术,任何进一步的手术干预都会导致后续炎症以及对PVR反应的持续刺激和进一步损害。

结论

遵循一些决定性的规则和技巧是成功复位PVR性视网膜脱离的前提条件。

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本文引用的文献

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Mechanisms of epithelial-mesenchymal transition in proliferative vitreoretinopathy.增殖性玻璃体视网膜病变中上皮-间质转化的机制
Discov Med. 2015 Oct;20(110):207-17.
2
Use of triamcinolone during vitrectomy surgery to visualize membranes and vitreous.在玻璃体切割手术中使用曲安奈德以观察视网膜前膜和玻璃体。
Clin Ophthalmol. 2008 Dec;2(4):891-6. doi: 10.2147/opth.s3434.