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利用尖叶木犀榄叶提取物生物合成银包覆氧化镁纳米复合材料及其光催化、抗氧化和抗菌活性。

Biosynthesis of silver capped magnesium oxide nanocomposite using Olea cuspidata leaf extract and their photocatalytic, antioxidant and antibacterial activity.

作者信息

Khan Afaq Ullah, Khan Arif Ullah, Li Baoshan, Mahnashi Mater H, Alyami Bandar A, Alqahtani Yahya S, Alqarni Ali O, Khan Zia Ul Haq, Ullah Sami, Wasim Muhammad, Khan Qudrat Ullah, Ahmad Waqas

机构信息

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China; Beijing Advaced Innovation Centre for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, PR China.

出版信息

Photodiagnosis Photodyn Ther. 2021 Mar;33:102153. doi: 10.1016/j.pdpdt.2020.102153. Epub 2020 Dec 25.

Abstract

Green chemistry is a modern area of research which covers synthesis of nanomaterials through useful, environmentally, economically friendly techniques and their use in different fields. The synthesis involves the formation of bimetallic nanomaterials to enhance their synergistic relationship and achieve special modulated properties. That's why bimetallic nanomaterials are extremely important and gaining interest among researchers in the field of medicinal chemistry for the treatment of various diseases. In this particular study, bimetallic nanoparticles synthesis was done by reduction procedure using leaf extract of Olea cuspidata. The phytochemicals in leaf extract act as stabilizing and capping agent in reduction of precursor's salts. The characterization of green synthesized Ag@MgO nanocomposite was done through several analytical techniques such as ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), High resolution transmission electron microscope (HRTEM) and Zeta potential. To explore the biological potential of synthesized nanocomposite, antibacterial activities against gram negative (Escherichia coli) bacteria and gram positive (Staphylococcus aureus) has been evaluated. The photocatalytic activity in contrary to methylene blue (MB) decomposition was seen efficiently. Moreover, the antioxidant nature of green synthesized Ag@MgO nanocomposite was analyzed by destabilizing and scavenging maximum percentage (93 %) of dangerous and harmful 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical. The best and surprising results provided the information for the presence of essential and vital components in Olea Cuspidata in the form of organic acids (Citrus Acid) aids in stabilizing the entire structure with enhanced properties. Up to the best of our knowledge, the facts and results obtained regarding the structure of Ag@MgO nanocomposite clearly illustrates the uniqueness of green chemistry and also its role in future developing multifunctional nanoparticles in the field of nanobiotechnology.

摘要

绿色化学是一个现代研究领域,它涵盖了通过有用的、环境友好和经济友好的技术合成纳米材料及其在不同领域的应用。该合成涉及双金属纳米材料的形成,以增强它们的协同关系并实现特殊的调制性能。这就是为什么双金属纳米材料极其重要,并在药物化学领域的研究人员中引起了对治疗各种疾病的兴趣。在这项具体研究中,使用尖叶油橄榄叶提取物通过还原程序合成了双金属纳米颗粒。叶提取物中的植物化学物质在前体盐的还原过程中充当稳定剂和封端剂。通过几种分析技术对绿色合成的Ag@MgO纳米复合材料进行了表征,如紫外可见(UV-vis)光谱、X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)、扫描电子显微镜(SEM)、高分辨率透射电子显微镜(HRTEM)和zeta电位。为了探索合成纳米复合材料的生物潜力,评估了其对革兰氏阴性(大肠杆菌)菌和革兰氏阳性(金黄色葡萄球菌)菌的抗菌活性。观察到其对亚甲基蓝(MB)分解具有高效的光催化活性。此外,通过使危险有害的2,2-二苯基-1-苦基肼(DPPH)自由基失稳并清除最大百分比(93%),分析了绿色合成的Ag@MgO纳米复合材料的抗氧化性质。最好且令人惊讶的结果提供了信息,表明尖叶油橄榄中以有机酸(柠檬酸)形式存在的必需和重要成分有助于稳定整个结构并增强其性能。据我们所知,关于Ag@MgO纳米复合材料结构获得的事实和结果清楚地说明了绿色化学的独特性及其在未来纳米生物技术领域开发多功能纳米颗粒中的作用。

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