Murata K, Yokoyama Y
Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Japan.
Blood Vessels. 1988;25(1):1-11. doi: 10.1159/000158716.
We examined the glycosaminoglycan (GAG) components in human pulmonary arteries compared to those in the aorta. Definite changes in GAG contents and components were found between the pulmonary arteries and the aorta. The GAG content of the aorta was constantly higher than that of the pulmonary artery. As to the components of the arterial GAGs, however, hyaluronic acid comprised significantly higher proportions of total GAGs in the pulmonary arteries than in the aorta, whereas dermatan sulfate showed lower proportions in the pulmonary arteries than in the aorta. These significant differences are possibly due to either the effect of the continuously different blood pressure on the wall of these two types of arterial vessels or to constitutional changes of their fundamental structures associated with atherosclerosis.
我们研究了人类肺动脉与主动脉中的糖胺聚糖（GAG）成分。发现肺动脉和主动脉之间的GAG含量及成分存在明显变化。主动脉的GAG含量始终高于肺动脉。然而，关于动脉GAG的成分，透明质酸在肺动脉中占总GAG的比例显著高于主动脉，而硫酸皮肤素在肺动脉中的比例低于主动脉。这些显著差异可能是由于这两种动脉血管壁上持续不同的血压作用，或者是与动脉粥样硬化相关的基本结构的体质变化。
