Wasfie T, Newman R
Department of Surgery, Harlem Hospital Center, College of Physicians and Surgeons of Columbia University, New York, New York 10037.
Cancer. 1988 Jan 1;61(1):167-72. doi: 10.1002/1097-0142(19880101)61:1<167::aid-cncr2820610128>3.0.co;2-h.
The majority of reports on laryngeal carcinoma are from institutions serving a mostly white population. This report is about laryngeal carcinoma in black patients at Harlem Hospital Center. In a retrospective analysis, 113 patients (male-female, 3.5:1) with carcinoma of the larynx were examined. Sixty-seven patients (59%) were between 50 and 60 years of age. There were two patients (2%) with carcinoma in situ, 15 (13%) in Stage I, 40 (35%) in Stage II, 39 (35%) in Stage III, and 15 (13%) in Stage IV. Of the 113 patients, 70 (62%) were treated surgically, Group I; 24 (21%) received radiotherapy only, Group 2; and 19 (17%) refused treatment or died before therapy initiation. For patients in Group 1, the 1-year survival rate was 68% (43 of 63), the 3-year survival rate was 38% (20 of 53), and the 5-year survival rate was 15% (7 of 47). For Group 2, the survival rate was 48% (11 of 23), 30% (7 of 23), and 14% (3 of 22), respectively. In this patient population, laryngeal carcinoma occurred at a younger age than other reported groups, had a higher incidence in females, and had a lower 1-, 3-, and 5-year survival rate.
大多数关于喉癌的报告来自主要服务于白人人口的机构。本报告是关于哈莱姆医院中心黑人患者的喉癌情况。在一项回顾性分析中，对113例喉癌患者（男女比例为3.5:1）进行了检查。67例患者（59%）年龄在50至60岁之间。有2例原位癌患者（2%），15例（13%）处于I期，40例（35%）处于II期，39例（35%）处于III期，15例（13%）处于IV期。在这113例患者中，70例（62%）接受了手术治疗，为第1组；24例（21%）仅接受了放疗，为第2组；19例（17%）拒绝治疗或在开始治疗前死亡。对于第1组患者，1年生存率为68%（63例中的43例），3年生存率为38%（53例中的20例），5年生存率为15%（47例中的7例）。对于第2组，生存率分别为48%（23例中的11例）、30%（23例中的7例）和14%（22例中的3例）。在这一患者群体中，喉癌发病年龄比其他报告的群体更年轻，女性发病率更高，1年、3年和5年生存率更低。
