Lee K, Strauss M
Department of Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio.
J Natl Med Assoc. 1994 Jul;86(7):530-4.
Our experience at University Hospitals of Cleveland (UHOC), Cuyahoga County, Ohio, led us to suspect an increased incidence of head and neck cancer in blacks. We reviewed our tumor registry records from 1975 to 1989 analyzing for age, sex, race, and head and neck site of disease. Head and neck cancers comprised 6.1% of all cancers at UHOC. This is in comparison with 3.7% of all cancers in Cuyahoga County and an estimated 5.5% nationally. This higher proportion of head and neck cancer was observed primarily in black men and women in whom these cancers made up 7.7% of all cancers compared with 5.7% in whites. Both black men and women had a higher percentage of these cancers out of all cancers for their respective sex and race than whites. For all head and neck cancer sites except the salivary glands, blacks were observed to be two to four times more likely than whites to be diagnosed before the age of 50 years (P < .01). These findings thus substantiated an increased incidence and earlier age of onset of head and neck cancers in blacks compared with whites.
我们在俄亥俄州库亚霍加县克利夫兰大学医院(UHOC)的经验使我们怀疑黑人头颈部癌症的发病率有所增加。我们回顾了1975年至1989年的肿瘤登记记录,分析了疾病的年龄、性别、种族以及头颈部发病部位。头颈部癌症占UHOC所有癌症的6.1%。相比之下,库亚霍加县所有癌症中头颈部癌症占3.7%,全国估计为5.5%。头颈部癌症的这一较高比例主要出现在黑人男性和女性中,这些癌症在黑人所有癌症中占7.7%,而在白人中占5.7%。黑人男性和女性头颈部癌症在各自性别和种族的所有癌症中所占百分比均高于白人。除唾液腺外,在所有头颈部癌症发病部位,观察到黑人在50岁之前被诊断出癌症的可能性是白人的两到四倍(P < 0.01)。因此,这些发现证实了与白人相比,黑人头颈部癌症的发病率增加且发病年龄更早。