Guo Zhaoyang, Liu Haiyang, Dai Wubin, Lei Yifeng
School of Power and Mechanical Engineering & the Institute of Technological Science, Wuhan University, Wuhan, 430072, China.
School of Material Science and Engineering, Wuhan Institute of Technology, Wuhan, 430205, China.
Smart Mater Med. 2020;1:54-65. doi: 10.1016/j.smaim.2020.07.001. Epub 2020 Jul 21.
Biosensing is a rising analytical field for detection of biological indicators using transducing systems. Smart materials can response to external stimuli, and translate the stimuli from biological domains into signals that are readable and quantifiable. Smart materials, such as nanomaterials, photonic crystals and hydrogels have been widely used for biosensing purpose. In this review, we illustrate the incorporation of smart materials in biosensing systems, including the design of responsive materials, their responsive mechanism of biosensing, and their applications in detection of four types of common biomolecules (including glucose, nucleic acids, proteins, and enzymes). In the end, we also illustrate the current challenges and prospective of using smart materials in biosensing research fields.
生物传感是一个新兴的分析领域，用于利用传感系统检测生物指标。智能材料能够响应外部刺激，并将来自生物领域的刺激转化为可读且可量化的信号。纳米材料、光子晶体和水凝胶等智能材料已被广泛用于生物传感目的。在本综述中，我们阐述了智能材料在生物传感系统中的应用，包括响应材料的设计、它们的生物传感响应机制，以及它们在检测四种常见生物分子（包括葡萄糖、核酸、蛋白质和酶）中的应用。最后，我们还阐述了在生物传感研究领域中使用智能材料的当前挑战和前景。
