Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Orthopaedic Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
J Korean Med Sci. 2020 Dec 21;35(49):e410. doi: 10.3346/jkms.2020.35.e410.
Periprosthetic joint infection (PJI) is the most serious complication after total joint arthroplasty. The incidence and burden of PJI in North America have been reported. There might be potential differences according to ethnics and regional practices between western countries and East Asia. Nevertheless, its incidence in East Asia remains unknown. We aimed to evaluate the incidence and economic burden of PJI in Korea and to project the future burden.
We identified numbers of total hip arthroplasties, total knee arthroplasties and PJIs in Korea from 2010 to 2018 using medical claim data of Korean Health Insurance and Review and Assessment. Annual incidence and medical cost of PJI were calculated. We projected future burden of PJI through 2030 using Quasi-poisson regression model.
The annual incidence of PJI ranged from 2.3% to 2.8% and the average cost per each PJI patient ranged from $4,361 to $6,016. Total annual cost of PJI increased from $8.0 million in 2010 to $18.0 million in 2018 and was projected to exceed $57.0 million by 2030.
The incidence of PJI in Korea is comparable with reported PJI incidence of 2.0%-2.7% in the United States. Our findings would be used for worldwide comparison of PJI epidemiology and establishment of healthcare policies for PJI in East Asia.
人工关节假体周围感染（PJI）是全关节置换术后最严重的并发症。北美已经报道了 PJI 的发病率和负担。西方国家和东亚之间可能存在种族和区域实践的差异。然而，东亚的发病率尚不清楚。我们旨在评估韩国 PJI 的发病率和经济负担，并预测未来的负担。
我们使用韩国健康保险和审查评估的医疗索赔数据，从 2010 年到 2018 年确定了韩国全髋关节置换术、全膝关节置换术和 PJI 的数量。计算了 PJI 的年发病率和医疗费用。我们使用拟泊松回归模型预测到 2030 年 PJI 的未来负担。
PJI 的年发病率范围为 2.3%至 2.8%，每位 PJI 患者的平均费用为 4361 美元至 6016 美元。PJI 的总年度费用从 2010 年的 800 万美元增加到 2018 年的 1800 万美元，并预计到 2030 年将超过 5700 万美元。
韩国 PJI 的发病率与美国报告的 2.0%-2.7%的 PJI 发病率相当。我们的研究结果将用于 PJI 流行病学的全球比较，并为东亚 PJI 的医疗保健政策制定提供依据。
